U
Uchenna H. Iloeje
Researcher at Bristol-Myers Squibb
Publications - 76
Citations - 11403
Uchenna H. Iloeje is an academic researcher from Bristol-Myers Squibb. The author has contributed to research in topics: Hepatitis B & Entecavir. The author has an hindex of 38, co-authored 75 publications receiving 10536 citations. Previous affiliations of Uchenna H. Iloeje include University of Washington & Alexion Pharmaceuticals.
Papers
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Journal ArticleDOI
Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
Chien-Jen Chen,Hwai I. Yang,Jun Su,C.-L. Jen,San Lin You,Sheng-Nan Lu,Guan-Tarn Huang,Uchenna H. Iloeje +7 more
TL;DR: Elevated serum HBV DNA level (> or =10,000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis.
Journal ArticleDOI
Predicting cirrhosis risk based on the level of circulating hepatitis B viral load.
Uchenna H. Iloeje,Hwai I. Yang,Jun Su,Chin Lan Jen,San Lin You,Chien-Jen Chen,Chien-Jen Chen +6 more
TL;DR: In this paper, the authors report on the relationship between hepatitis B viremia and progression to cirrhosis in chronic hepatitis B infection and show that progression to liver failure in hepatitis B-infected persons is correlated with the level of circulating virus.
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Long‐term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B
Ting-Tsung Chang,Yun Fan Liaw,Shun Sheng Wu,Eugene R. Schiff,Kwang Hyub Han,Ching-Lung Lai,Rifaat Safadi,Samuel S. Lee,Waldemar Halota,Zachary Goodman,Yunchan Chi,Hui Zhang,R. Hindes,Uchenna H. Iloeje,Suzanne Beebe,Bruce Kreter +15 more
TL;DR: The majority of nucleoside‐naive patients with CHB who were treated with entecavir in this long‐term cohort achieved substantial histological improvement and regression of fibrosis or cirrhosis.
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Global epidemiology of hepatitis B virus.
Brian Custer,Sean D. Sullivan,Thomas K. Hazlet,Uchenna H. Iloeje,David L. Veenstra,Kris V. Kowdley +5 more
TL;DR: HBV vaccination programs will decrease the future global burden of HBV infection and evidence of reduced burden is mounting in country-specific populations, but vaccination programs have still not been implemented in all countries, thereby maintaining reservoirs of infection and continued HBV transmission.
Journal ArticleDOI
Associations Between Hepatitis B Virus Genotype and Mutants and the Risk of Hepatocellular Carcinoma
Hwai I. Yang,Shiou-Hwei Yeh,Pei-Jer Chen,Pei-Jer Chen,Uchenna H. Iloeje,Chin Lan Jen,Jun Su,Li Yu Wang,Sheng Nan Lu,San Lin You,Ding-Shinn Chen,Yun Fan Liaw,Chien-Jen Chen +12 more
TL;DR: HBV genotype C and specific alleles of BCP and precore were associated with risk of HCC, and these associations were independent of serum HBV DNA level.