U
Undurti N. Das
Researcher at Bharati Vidyapeeth University
Publications - 7
Citations - 330
Undurti N. Das is an academic researcher from Bharati Vidyapeeth University. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 6, co-authored 7 publications receiving 300 citations.
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Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules
TL;DR: It is proposed that a rational combination of ω-3 and ψ-6 fatty acids and the co-factors that are necessary for their appropriate action/metabolism is as beneficial as that of the combined use of a statin, thiazide, a β blocker, and an angiotensin converting enzyme (ACE) inhibitor, folic acid, and aspirin.
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Colorectal cancer cell growth inhibition by linoleic acid is related to fatty acid composition changes.
TL;DR: Results showed that one of the mechanisms by which supplementation of LA induces cancer cell death could be altering the ratio of n-6/n-3 PUFAs, and this may be related to cell differentiation status.
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Free Zn2+ enhances inhibitory effects of EGCG on the growth of PC-3 cells
Shi-li Sun,Guo-qing He,Haining Yu,Jun-guo Yang,Devajit Borthakur,Lan-cui Zhang,Shengrong Shen,Undurti N. Das +7 more
TL;DR: Results indicate that though Zn2+ enhanced the action of EGCG on PC-3 cells, zinc-EGCG complex is highly unlikely to be formed in the presence of Zn1+ and EGCg to explain the potentiating action of ZN2+ on the growth inhibitory property of E GCG onPC- 3 cells.
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Mechanism of Free Zn(2+) Enhancing Inhibitory Effects of EGCG on the Growth of PC-3 Cells: Interactions with Mitochondria
Jun-guo Yang,Haining Yu,Shi-li Sun,Lan-cui Zhang,Undurti N. Das,Hui Ruan,Guoqing He,Shengrong Shen +7 more
TL;DR: It is suggested that E GCG, Zn2+, and EGCG + Zn 2+ induce necrosis or apoptosis of PC-3 cells through mitochondria-mediated apoptotic pathway and free Zn1+-enhanced effects of EGCGs on PC- 3 cells due to its interactions with mitochondria.
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Gene and protein expression profiling of the fat-1 mouse brain.
Dalma Ménesi,Klára Kitajka,Eszter Molnár,Zoltán Kis,Jérome Belleger,Michael Narce,Jing X. Kang,László G. Puskás,Undurti N. Das +8 more
TL;DR: Gene expression profile, RT-PCR and protein microarray studies in the hippocampus and whole brain of wild-type and fat-1 transgenic mice revealed that genes and proteins concerned with inflammation, apoptosis, neurotransmission, and neuronal growth and synapse formation are specifically modulated infat-1 mice, which may explain why n-3 PUFAs are of benefit in the prevention and treatment of diseases such as Alzheimer's disease, schizophrenia and other diseases associated with neuronal dysfunction.