Venous aneurysms: Surgical indications and review of the literature

• During a ten-year period, 92 patients underwent an umbilical herniorrhaphy. Patients were divided into three groups: group 1, cirrhotic patients with ascites with functioning peritoneovenous shunts (n=15); group 2, cirrhotic patients with ascites with nonfunctioning or no peritoneovenous shunts (n = 24); and group 3, noncirrhotic patients (n = 53). The charts were analyzed for postoperative mortality and morbidity and recurrence of the umbilical hernia. Umbilical hernia in cirrhotic patients with uncontrolled ascites was associated with significant mortality (8.3%) and morbidity (16.6%) and a significantly greater incidence of recurrence (16.6%). Umbilical herniorrhaphy in patients with functioning peritoneovenous shunts was associated with minimal morbidity (7%). These data suggest that cirrhotic patients with ascites who require an umbilical herniorrhaphy preferably should undergo peritoneovenous shunting before repair of the hernia. ( Arch Surg 1984;119:442-445)

Umbilical Herniorrhaphy in Cirrhotic Patients

Cerebellar ataxia can be induced by a large number of drugs. We here conducted a systemic review of the drugs that can lead to cerebellar ataxia as an adverse drug reaction (ADR). We performed a systematic literature search in Pubmed (1966 to January 2014) and EMBASE (1988 to January 2014) to identify all of the drugs that can have ataxia as an ADR and to assess the frequency of drug-induced ataxia for individual drugs. Furthermore, we collected reports of drug-induced ataxia over the past 20 years in the Netherlands by querying a national register of ADRs. Drug-induced ataxia was reported in association with 93 individual drugs (57 from the literature, 36 from the Dutch registry). The most common groups were antiepileptic drugs, benzodiazepines, and antineoplastics. For some, the number needed to harm was below 10. Ataxia was commonly reversible, but persistent symptoms were described with lithium and certain antineoplastics. It is important to be aware of the possibility that ataxia might be drug-induced, and for some drugs the relative frequency of this particular ADR is high. In most patients, symptoms occur within days or weeks after the introduction of a new drug or an increase in dose. In general, ataxia tends to disappear after discontinuation of the drug, but chronic ataxia has been described for some drugs.

Drug-induced cerebellar ataxia: a systematic review

Acute ataxia is a fairly common emergency that confronts the pediatric neurologist in daily life. The differential diagnosis of acute pediatric ataxia is wide, but informed history and careful clinical examination can narrow it and help target investigations. This review discusses various etiologies of acute pediatric ataxia, focusing on clinical presentation, diagnostic considerations, and approach to investigation. Aspects of treatment and prognosis are also mentioned. Diseases with potentially high morbidity and mortality, such as acute cerebellitis, opsoclonus-myoclonus syndrome, and cerebellar stroke, receive particular attention.

Acute ataxia in children: approach to clinical presentation and role of additional investigations.

A false venous aneurysm of the axilla following minoor trauma is described. The previously reported cases are reviewed and aetiology and diagnosis of this uncommon, condition discussed.

Vaidya Pn

Papers

Venous aneurysms (a case report).

Unusual cerebellar ataxia.

Spontaneous temporary relief of ascites in liver cirrhosis. A case report.