V
Van Damme
Researcher at Radboud University Nijmegen
Publications - 2
Citations - 25
Van Damme is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Neurite & Chemistry. The author has an hindex of 1, co-authored 2 publications receiving 1 citations.
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Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition
Stoklund Dittlau,Krasnow,Fumagalli,Vandoorne,Baatsen,Kerstens,Giacomazzi,Pavie,Sampaolesi,Van Damme,van den Bosch +10 more
TL;DR: It is observed that ALS-causing FUS mutations resulted in a reduced neurite outgrowth and in a decreased NMJ number, further prompting HDAC6 inhibition as a potential therapeutic strategy for ALS.
Posted ContentDOI
Chemical Reversible Crosslinking Enables Measurement of RNA 3D Distances and Alternative Conformations in Cells
TL;DR: ShARC as mentioned in this paper uses chemical crosslinkers of defined lengths to measure distances between nucleotides in cellular RNA, enabling transcriptome-wide tertiary structure contact maps at high accuracy and precision, revealing heterogeneous RNA structures and interactions.