V
Vinay Kumar Pathak
Publications - 11
Citations - 92
Vinay Kumar Pathak is an academic researcher. The author has contributed to research in topics: Mycobacterium leprae & Leprosy. The author has an hindex of 6, co-authored 9 publications receiving 64 citations.
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VDR polymorphism, gene expression and vitamin D levels in leprosy patients from North Indian population.
Itu Singh,Mallika Lavania,Vinay Kumar Pathak,Madhvi Ahuja,Ravindra P. Turankar,Vikram Singh,Utpal Sengupta +6 more
TL;DR: Blood levels of vitamin D do not play any role in clinical manifestations of any forms of leprosy, and association of t-F-a haplotype with leProsy was found to be significant and could be used as a genetic marker to identify individuals at high risk for developing leproSy.
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Molecular detection of multidrug-resistant Mycobacterium leprae from Indian leprosy patients.
Mallika Lavania,Itu Singh,Ravindra P. Turankar,Madhvi Ahuja,Vinay Kumar Pathak,Utpal Sengupta,Loretta Das,Archana Kumar,Joydeepa Darlong,Rajeev Nathan,Asha Maseey +10 more
TL;DR: This study showed the emergence of MDR M. leprae in MDT-treated leprosy patients from endemic regions of India with confirmed resistance to rifampicin, dapsone and ofloxacin.
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Addition of Mycobacterium indicus pranii vaccine as an immunotherapeutic to standard chemotherapy in borderline leprosy: a double-blind study to assess clinical improvement (preliminary report).
TL;DR: The response of leprosy patients to chemotherapy (WHO-Multi Drug Therapy) though generally good and predictable, exhibits variations in a section of cases, some cases show a dramatic response while others show a slower response such variations are a reflection of the immune status of the host.
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Utility of multiplex PCR for early diagnosis and household contact surveillance for leprosy.
Vinay Kumar Pathak,Itu Singh,Ravindra P. Turankar,Mallika Lavania,Madhvi Ahuja,Vikram Singh,Utpal Sengupta +6 more
TL;DR: There is an increase in overall diagnostic positivity for M. leprae DNA detection by M-PCR as compared to individual PCR, suggesting the utility of M- PCR for early diagnosis and household contact surveillance for leprosy.
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Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins.
Itu Singh,Asha Ram Yadav,Keshar Kunja Mohanty,Kiran Katoch,Prashant Sharma,Vinay Kumar Pathak,Deepa Bisht,Umesh D. Gupta,Utpal Sengupta +8 more
TL;DR: The data suggest that these mimicking proteins tropomyosin and ATP-dependent Clp protease ATP-binding subunit of M. leprae or more precisely mimicking epitopes (four B cell epitopes) might be responsible for extensive tissue damage during type1 reaction in leprosy.