Vincent T. Armenti

TL;DR: Key benefits of the NTPR are the personal contact between registry staff and participants, the wide range of pregnancy-related variables that are analyzed, and the opportunity for health-care providers to obtain information that helps them care for transplant recipients on a case-by-case basis.

TL;DR: A higher incidence of structural malformations was seen with MMF exposures during pregnancy compared to the overall kidney transplant recipient offspring, while no structural defects have as yet been reported with early pregnancy sirolimus exposures.

TL;DR: Outcomes of pregnancies from 115 female kidney transplant recipients maintained on cyclosporine before and during pregnancy were obtained from questionnaires, hospital records, and telephone interviews and there was a trend toward lower birth-weight in infants of diabetic recipients.

TL;DR: The National Transplantation Pregnancy Registry (NTPR) was established in 1991 to study the outcomes of pregnancies in female transplant recipients and pregnancies fathered by male transplant recipients, and newer information points to an increased need for vigilance among centers and continued monitoring of pregnancy outcomes in this population.

TL;DR: Current data from the literature, as well as from reports from the National Transplantation Pregnancy Registry, support the concept that immuno suppression be maintained at appropriate levels during pregnancy.