Vito R. Petretta

TL;DR: Genetic anomalies can be considered the primary cause of myocardial damage in carriers of dystrophinopathic myopathies and shows the same behavior already described in DMD and BMD patients and progresses from preclinical to dilated cardiomyopathy, passing through stages ofMyocardial hypertrophy or dysrhythmias.

TL;DR: Signs of hypoxic myocardial damage occurred in beta-, gamma- and delta-sarcoglycanopathies, while initial signs of a dilated cardiomyopathy in gamma-and delta-Sarcogly canopathies were found.

TL;DR: It is confirmed that cardiac dysfunction is a primary feature of Becker muscular dystrophy and that a real, dilated cardiomyopathy is the most frequent type of myocardial involvement after the age of 20.

TL;DR: Within the Campania region of southern Italy a prospective study on X‐linked progressive muscular dystrophy was conducted over a period of 12 years from 1969 to 1980, inclusive, which includes the effects of age on physical performance, serum creatine kinase activity and serum myoglobin levels, the types of cardiac damage, and the causes of death.

TL;DR: The correlations between the type of gene mutation and the cardiac clinical picture were examined in 284 patients with dystrophinopathy and the age of death was 18 years in DMD patients with deletions including 48-49 whereas the age was about 22 in the cases with other deletions.