Showing papers by "Vladimir S. Prassolov published in 2001"
TL;DR: The results suggest that in articular chondrocytes the GSNO-induced VEGF gene transcriptional activation is dependent on endogenous ROS production and oxidative thiol modifications, and not on dibutyryl cGMP, a non-hydrolyzable analog of cG MP.
15 citations
TL;DR: Interference assays with M813 and viruses from four interference groups of MuLV reveal a novel receptor interference group of type C MuLVs that must use a distinct receptor for cell entry, and substitution of M8 13env sequences in Moloney MuLV resulted in a replication-competent virus.
Abstract: Murine leukemia virus (MuLV) M813 was originally isolated from the Southeast Asian rodent Mus cervicolor. As with the ecotropic MuLVs derived from Mus musculus, its host range is limited to rodent cells. Earlier studies have mapped its receptor to chromosome 2, but it has not been established whether M813 shares a common receptor with any other MuLVs. In this study, we have performed interference assays with M813 and viruses from four interference groups of MuLV. The infection efficiency of M813 was not compromised in cells expressing any one of the other MuLVs, demonstrating that M813 must use a distinct receptor for cell entry. The entire M813 env coding region was molecularly cloned. Sequence analysis revealed high similarity with other MuLVs but with a unique receptor-binding domain. Substitution of M813 env sequences in Moloney MuLV resulted in a replication-competent virus with a host range and interference profile similar to those of the biological clone M813. M813 thus defines a novel receptor interference group of type C MuLVs.
14 citations