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W.M. Gayashani Sandamalika
Researcher at Jeju National University
Publications - 17
Citations - 84
W.M. Gayashani Sandamalika is an academic researcher from Jeju National University. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 3, co-authored 10 publications receiving 39 citations.
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Journal ArticleDOI
Molecular characterization of kappa class glutathione S-transferase from the disk abalone (Haliotis discus discus) and changes in expression following immune and stress challenges.
W.M. Gayashani Sandamalika,Thanthrige Thiunuwan Priyathilaka,D.S. Liyanage,Sukkyoung Lee,Han-Kyu Lim,Jehee Lee +5 more
TL;DR: It is suggested that AbGST&kgr; is involved in detoxification and immunological host defense mechanisms and allows abalones to overcome stresses in order for them to have an increased chance of survival.
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The possible role of catalase in innate immunity and diminution of cellular oxidative stress: Insights into its molecular characteristics, antioxidant activity, DNA protection, and transcriptional regulation in response to immune stimuli in yellowtail clownfish (Amphiprion clarkii).
TL;DR: In this article, the identification and characterization of a catalase homolog from Amphiprion clarkii (ClCat), followed by its functional characterization was reported, concluding that rClCat plays an essential role in maintaining cellular oxidative homeostasis and host immune protection.
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Immune and xenobiotic responses of glutathione S-Transferase theta (GST-θ) from marine invertebrate disk abalone (Haliotis discus discus): With molecular characterization and functional analysis
W.M. Gayashani Sandamalika,Thanthrige Thiunuwan Priyathilaka,Seongdo Lee,Hyerim Yang,Jehee Lee +4 more
TL;DR: Records are provided for the detoxification ability and the immunological host defensive capability of AbGST-θ in disk abalone and GST theta under different stress conditions with special reference to post immune challenges.
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Molecular characterization and functional analysis of glutathione S-transferase kappa 1 (GSTκ1) from the big belly seahorse (Hippocampus abdominalis): Elucidation of its involvement in innate immune responses
Anushka Vidurangi Samaraweera,W.M. Gayashani Sandamalika,D.S. Liyanage,Sukkyoung Lee,Thanthrige Thiunuwan Priyathilaka,Jehee Lee +5 more
TL;DR: The plausible important role of HaGSTκ1 in innate immunity and detoxification of harmful xenobiotics is proposed and its biochemical and functional properties were analyzed.
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Quadruple domain-containing galectin from marine invertebrate disk abalone (Haliotis discus discus): Molecular perspectives in early development, immune expression, and potent antiviral responses.
TL;DR: The findings reveal the potent antiviral responses of molluscan quadruple domain-containing galectin, AbGalec, along with its involvement in innate immunity.