The aim of this study was to investigate the effect of ingestion of ice slurry before bedtime on the sleep quality of rugby union players in the summer season. Thirteen healthy male university rugby union players volunteered for this study. The participants ingested either ice slurry or a room-temperature beverage (control) 30 min before bedtime. A wearable activity-based sleep monitor was used to analyze objective sleep parameters, and the subjective sleep scores were assessed using the Oguri–Shirakawa–Azumi Sleep Inventory, middle-aged and aged version (OSA-MA). No differences in the amount or efficiency of sleep were observed between the ice slurry/control beverage conditions. Significant shortening of the sleep latency was observed in the ice slurry condition as compared with the control beverage condition. Moreover, significant improvement of the subjective sleep score for “feeling refreshed” on the OSA-MA was observed in the ice slurry condition. There were no significant differences in the other subjective sleep scores between the two conditions. The results suggest that ice slurry ingestion before bedtime may improve the latency of sleep onset, accelerate recovery from fatigue, and be useful as a sleep improvement strategy in rugby union players engaging in exercises during the summer season.

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Effect of Ingestion of Ice Slurry on the Sleep Quality of Rugby Union Players in the Summer Season

Introduction Improving the quality of sleep may promote enhanced recovery in surgical patients. In addition to controversial or conflicting study conclusions, the current clinical studies on pharmacotherapy for improving postoperative sleep quality are mostly limited to evaluating the effect of a specific drug or supplement compared with placebo, and they lack comparisons between drugs or supplements. Therefore, we plan to conduct a systematic review and network meta-analysis to compare the efficacy of different drugs or supplements for improving postoperative sleep quality. Methods and analysis We will search the MEDLINE, Embase, Cochrane Central Register of Controlled Trials, CNKI and Wanfang databases from the dates of their inception to December 2022. We will only include randomised controlled trials, irrespective of language and publication status. The primary outcome is postoperative sleep quality assessed by any validated tools or polysomnography. We will assess the quality of all included trials according to version 2 of the Cochrane risk-of-bias tool for randomised trials. We will use the GeMTC package of R software to perform direct and indirect comparisons via a Bayesian framework using a random-effects model. We will use the Confidence in Network Meta-Analysis approach to evaluate the quality of evidence. Ethics and dissemination Ethical approval is not required for this protocol because we will only be pooling published data. We plan to submit our review to academic conferences and peer-reviewed academic journals. PROSPERO registration number CRD42022356508.

/pdf/pharmacotherapy-for-improving-postoperative-sleep-quality-a-2h5oygcr.pdf

Pharmacotherapy for improving postoperative sleep quality: a protocol for a systematic review and network meta-analysis

BACKGROUND The aim of this study was to measure sleep quality among patients who underwent infective endocarditis (IE) surgery and identify the risk factors involved in sleep disorders. MATERIAL AND METHODS In this study, we used actigraphy, the Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleep Scale (ESS) to determine the clinical characteristics of sleep disorders in 116 patients with IE who were in rehabilitation after surgery. RESULTS Our results showed that 46 (39.7%) patients had sleep efficiency over 85%, while 70 (60.3%) patients had sleep efficiency below 85%. The correlation analysis showed that sleep efficiency was related to the duration of the disease, with a longer duration leading to lower sleep efficiency (P=0.031). The sleep efficiency of patients with IE following surgery was also affected by alcohol consumption; however, surprisingly, patients with "heavy" alcohol consumption had higher sleep efficiency (P=0.030). We found a significant correlation between sleep efficiency and postoperative interleukin-6 (IL) levels, C-reactive protein (CRP) levels, and preoperative erythrocyte sedimentation rate (P<0.05). No significant correlation was found between brain natriuretic peptide levels and sleep efficiency, PSQI score, or ESS score. Postoperative hemoglobin (Hb) level was associated with sleep efficiency (R=0.194, P=0.036), but there was no statistically significant correlation between the PSQI and ESS scores. Postoperative alanine transaminase (ALT) showed a significant negative correlation with sleep efficiency (R=-0.27, P=0.003). CONCLUSIONS We found a high prevalence of sleep disorders in patients with IE along with an increase in inflammatory factors, including postoperative IL-6, CRP, ALT, and Hb levels.

The Assessment of Sleep Quality in Patients Following Valve Repair and Valve Replacement for Infective Endocarditis: A Retrospective Study at a Single Center.

The objective of this study was to investigate the efficacy of zolpidem for improving post-operative sleep quality among patients with infective endocarditis (IE) and to identify the potential risk factors for impaired sleep quality at 6 months after surgery. Patients with IE who underwent surgical treatment were divided into two groups according to zolpidem usage. The Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) were used to evaluate patients’ sleep quality and daytime sleepiness at baseline, which was the second day after transferal, and at 6 months after surgery. Logistic regression was used to identify potential risk factors. There were 32 patients in the zolpidem group and 42 in the control group. The PSQI and ESS scores at 6 months after surgery were significantly lower than those at baseline in both groups (P = 0.04). Additionally, 9 patients (28%) in the zolpidem group and 22 patients (52%) in the control group suffered poor sleep quality. Multivariate analysis identified age (odds ratio [OR] = 1.26, 95% confidence interval [CI]: 1.12–1.42), baseline PSQI score (OR = 2.66, 95%CI: 1.55–4.65), and no zolpidem usage (OR = 45.48, 95%CI: 3.01–691.23) as independent factors for poor sleep quality. Poor sleep quality after IE surgery was prevalent among patients even 6 months after IE surgery. Age, baseline PSQI score and no zolpidem usage were independently associated with poor sleep quality. Therefore, zolpidem has the potential to be an effective part of a treatment arsenal for poor sleep quality after surgical treatment for IE.

Zolpidem improves patients' sleep quality after surgical treatment for infective endocarditis: a prospective observational study

Analysis of sleep characteristics and clinical outcomes of 139 adult patients with infective endocarditis after surgery

W W Wei

Papers

The Assessment of Sleep Quality in Patients Following Valve Repair and Valve Replacement for Infective Endocarditis: A Retrospective Study at a Single Center.

Zolpidem improves patients' sleep quality after surgical treatment for infective endocarditis: a prospective observational study

Analysis of sleep characteristics and clinical outcomes of 139 adult patients with infective endocarditis after surgery.