W
Wanda Peczyńska-Czoch
Researcher at Wrocław University of Technology
Publications - 28
Citations - 904
Wanda Peczyńska-Czoch is an academic researcher from Wrocław University of Technology. The author has contributed to research in topics: Quinoline & Topoisomerase. The author has an hindex of 16, co-authored 28 publications receiving 826 citations.
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Journal ArticleDOI
Synthesis and structure-activity relationship of methyl-substituted indolo[2,3-b]quinolines: novel cytotoxic, DNA topoisomerase II inhibitors.
TL;DR: It is found that the antimicrobial and cytotoxic activity of indolo[2,3-b]quinolines was strongly influenced by the position, and the number of methyl substituents and the presence of methyl group at pyridine nitrogen was essential for the cytotoxicity of these compounds.
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Immobilization of wood-rotting fungi laccases on modified cellulose and acrylic carriers
TL;DR: The immobilized C. unicolor laccase exhibited the highest enzymic activity at pH 5.2 and it was more resistant to thermal denaturation than the native enzyme and more stable during storage at 4 °C: after 4 months the immobilized lacc enzyme retained 98% of initial activity.
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On the use of Trametes versicolor laccase for the conversion of 4-methyl-3-hydroxyanthranilic acid to actinocin chromophore
Jarosław Osiadacz,Abdulkareem J.H. Al-Adhami,Dorota Bajraszewska,Peter Fischer,Wanda Peczyńska-Czoch +4 more
TL;DR: Laccase isolated from Trametes versicolor was immobilized in polyacrylamide gel and used for the conversion of 4-methyl-3-hydroxyanthranilic acid to 2-amino-4,6-dimethyl-3
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Synthesis, and cytotoxic activity of some novel indolo[2,3-b]quinoline derivatives: DNA topoisomerase II inhibitors
Lukasz Kaczmarek,Wanda Peczyńska-Czoch,Osiadacz J,Marian Mordarski,W. Andrzej Sokalski,Janusz Boratyński,Ewa Marcinkowska,Halina Glazman-Kuśnierczyk,Czeslaw Radzikowski +8 more
TL;DR: A series of new 5H-indolo[2,3-b]quinoline derivatives bearing methoxy and methyl groups at C-2 and C-9 was synthesized and evaluated for their antimicrobial and cytotoxic activity.
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Catalytic Oxidative Cyclocondensation of o‐Aminophenols to 2‐Amino‐3H‐phenoxazin‐3‐ones
Mirosław Giurg,Katarzyna Piekielska,Magdalena Gebala,Bartosz Ditkowski,Marcin. Wolański,Wanda Peczyńska-Czoch,Jacek Młochowski +6 more
TL;DR: The catalytic oxidative cyclocondensation of oaminophenols was investigated in this paper, where the oxidants used were air/laccase, horseradish peroxidase, H2O2/ebselen, and TBHP/diphenyl diselenide 4.