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Wei Jiong Chen
Researcher at Shanghai Maritime University
Publications - 141
Citations - 489
Wei Jiong Chen is an academic researcher from Shanghai Maritime University. The author has contributed to research in topics: Medicine & Biology. The author has co-authored 1 publications.
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Journal ArticleDOI
Bifidobacterium longum mediated tryptophan metabolism to improve atopic dermatitis via the gut-skin axis
Zhifeng Fang,Tong Pan,Lingzhi Li,Hongchao Wang,Jinlin Zhu,Hao Zhang,Jianxin Zhao,Wei Jiong Chen,Wenwei Lu +8 more
TL;DR: The results suggested that based on the interactions of the gut-skin axis, B. longum CCFM1029 upregulated tryptophan metabolism and produced I3C to activate AHR-mediated immune response, alleviating AD symptoms.
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Ellagic acid and intestinal microflora metabolite urolithin A: A review on its sources, metabolic distribution, health benefits, and biotransformation.
Mengwei Zhang,Shumao Cui,Bingyong Mao,Qiuxiang Zhang,Jianxin Zhao,Hao Zhang,Xin Tang,Wei Jiong Chen +7 more
TL;DR: The source and metabolic pathway of ellagic tannins, and the mechanisms of the biological function of a metabolite, urolithin A, are discussed and the current strategies of biotransformation to obtain urolithsin A are expounded to provide ideas for further studies on the relationship between urologyithin and human health.
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Human gut microbiome aging clocks based on taxonomic and functional signatures through multi-view learning
Yutao Chen,Hongchao Wang,Wenwei Lu,Tong Wu,Weiwei Yuan,Jinlin Zhu,Yuan-Kun Lee,Jianxin Zhao,Hao Zhang,Wei Jiong Chen +9 more
TL;DR: An ensemble model with multiple heterogeneous algorithms and combined species and pathway profiles for multi-view learning will allow greater understanding of the interaction between microorganisms and age to realize the targeted intervention of aging.
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Bifidobacterium breve and Bifidobacterium longum Attenuate Choline-Induced Plasma Trimethylamine N-Oxide Production by Modulating Gut Microbiota in Mice
Qianqian Wang,Min Guo,Yang Liu,Mengshu Xu,Liu Shi,Xiu Li,Jianxin Zhao,Hao Zhang,Gang Wang,Wei Jiong Chen +9 more
TL;DR: The effect of Bifidobacterium strains on Bacteroides also suggests a relationship between the abundance of this genus and TMA concentrations in the gut, and may have therapeutic potential for alleviating TMAO-related diseases.
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Specific Strains of Faecalibacterium prausnitzii Ameliorate Nonalcoholic Fatty Liver Disease in Mice in Association with Gut Microbiota Regulation
Wen-Yi Hu,Wenying Gao,Zong-li Liu,Zhifeng Fang,Hongchao Wang,Jianxin Zhao,Hao Zhang,Wenwei Lu,Wei Jiong Chen +8 more
TL;DR: Five F. prausnitzii strains significantly restored serum lipid profiles and ameliorated glucose intolerance, adipose tissue dysfunction, hepatic steatosis, inflammation, and oxidative stress in a mouse model of NAFLD, indicating their potential as probiotic agents forNAFLD treatment.