A hexanuclear Ni(II) complex of 1-[(2-carboxymethyl)benzene]-3-[2-pyridine] triazene

pH-controlled synthesis of an aromatic triazene and its copper(II) complexation accompanied by an unexpected aromatic ring halogenation

The reaction of CuCl2·2H2O with 3,5-diisopropylpyrazole (PziPr2H) in the presence of sodium parafluorobenzoate (Na-p-FBz) resulted in the formation of an oxo-chloro-bridged tetranuclear complex [Cu4(PziPr2H)4(μ-O)(μ-Cl)6] 1, whereas the reaction of Cu(NO3)2·3H2O with PziPr2H in the presence of different benzoates gave [Cu(PziPr2H)2(μ-OCH3)]2(NO3)2
 2, [Cu(PziPr2H)3(NO3)(p-ClBz)]·CH3CN 3, [Cu(p-CH3Bz)2(PziPr2H)]2·2CH3CN 4, [Cu(p-OCH3Bz)2(CH3CN)]2·4CH3CN 5 and [Cu(p-CNBz)(CH3CN)]2
 6. Single-crystal X-ray diffraction studies confirmed these formulations. DNA binding studies for these complexes were performed by means of UV-visible absorption titration and viscosity measurements. Gel electrophoresis studies showed that hydroxyl radicals are involved in DNA cleavage in the presence of the complexes.

Synthesis and structural studies of some copper-benzoate complexes

The reaction of methyl anthranilate, sodium nitrite, and 2-aminopyridine produces a triazenide, namely, 1-[(2-carboxymethyl)benzene]-3-[2-pyridine]triazene (HL). In the presence of Et3N, the reaction of HL and CuCl2·2H2O gives a μ4-oxo-bridged tetranuclear copper(II) complex [Cu4OL3Cl3]·1.5THF (1·1.5THF), which has been characterized by X-ray crystallography and magnetic susceptibility measurements.

Wei Li

Papers

Synthesis, structure, and magnetic properties of a tetranuclear copper(fII) complex with a triazenido ligand