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Weidong Fei
Researcher at Zhejiang University
Publications - 50
Citations - 822
Weidong Fei is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 11, co-authored 32 publications receiving 308 citations. Previous affiliations of Weidong Fei include Zhejiang Chinese Medical University.
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The role of short-chain fatty acids in immunity, inflammation and metabolism
TL;DR: Theoretical basis for the study of SCFAs as potential drugs to promote human health is provided, which provides a systematic theoretical basis for studying the potential role ofSCFAs in regulating energy homeostasis and metabolism.
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Dual GSH-exhausting sorafenib loaded manganese-silica nanodrugs for inducing the ferroptosis of hepatocellular carcinoma cells.
Hongxia Tang,Danfei Chen,Chaoqun Li,Caihong Zheng,Xiaodong Wu,Yue Zhang,Qianqian Song,Weidong Fei +7 more
TL;DR: A new one-pot reaction for the synthesis of manganese doped mesoporous silica nanoparticles (MMSNs) which could induce ferroptosis of the tumor cells through the consumption of intracellular GSH caused by the degradation of MMSNs is introduced.
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RGD conjugated liposome-hollow silica hybrid nanovehicles for targeted and controlled delivery of arsenic trioxide against hepatic carcinoma
Weidong Fei,Yan Zhang,Han Shunping,Jiaoyang Tao,Hongyue Zheng,Yinghui Wei,Jiazhen Zhu,Fanzhu Li,Xuanshen Wang +8 more
TL;DR: The strategy of constructing a nanocarrier with targeted delivery and controlled release characteristics is prospective to enhance the antitumor effect of ATO.
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Targeted GSH-exhausting and hydroxyl radical self-producing manganese–silica nanomissiles for MRI guided ferroptotic cancer therapy
Weidong Fei,Danfei Chen,Hongxia Tang,Chaoqun Li,Weizeng Zheng,Feng-Ying Chen,Qianqian Song,Yunchun Zhao,Yu Zou,Caihong Zheng +9 more
TL;DR: F folate-PEG modified dihydroartemisinin (DHA) loaded manganese doped mesoporous silica nanoparticles (described as nanomissiles) were constructed and suppressed tumor metastasis by destroying the structure of polyunsaturated fatty acids in the cell membranes and showed potent antitumor activity.
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pH-triggered sustained release of arsenic trioxide by polyacrylic acid capped mesoporous silica nanoparticles for solid tumor treatment in vitro and in vivo.
Xuecheng Xiao,Liu Yangyang,Guo Manman,Weidong Fei,Hongyue Zheng,Zhang Rongrong,Yan Zhang,Yinghui Wei,Guohua Zheng,Fanzhu Li +9 more
TL;DR: It is suggested that the polyacrylic acid capped mesoporous silica nanoparticles (PAA-MSN) will be a promising nanocarrier for improving pharmacokinetic features and enhancing the anti-tumor efficacy of arsenic trioxide.