W
Wen Zhang
Researcher at Fudan University
Publications - 12
Citations - 108
Wen Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 4 publications receiving 82 citations. Previous affiliations of Wen Zhang include Xi'an Jiaotong University.
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Journal ArticleDOI
Association between thyroid stimulating hormone receptor gene intron polymorphisms and autoimmune thyroid disease in a Chinese Han population
TL;DR: Data suggest that the polymorphisms of rs12101255 and rs3783938 are associated with GD and HT, respectively.
Journal ArticleDOI
Aberrant expression of miRNA and mRNAs in lesioned tissues of Graves' disease.
Qiu Qin,Xuan Wang,Ni Yan,Rong-hua Song,Tian-tian Cai,Wen Zhang,Li-juan Guan,Fatuma-Said Muhali,Jin-an Zhang +8 more
TL;DR: The possibility that miRNA-target gene network may be involved in the pathogenesis of GD and could provide new insights into understanding the pathophysiological mechanisms of GD is highlighted.
Journal ArticleDOI
Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease
Ni Yan,Jiao-zhen Zhou,Jin-an Zhang,Tian-tian Cai,Wen Zhang,Yuan Wang,Fatuma-Said Muhali,Li-juan Guan,Rong-hua Song +8 more
TL;DR: It is suggested that histone acetylation modifications are aberrant in PBMCs of GD patients, possibly due to the deregulation of epigenetic modifier genes.
Journal ArticleDOI
Proteomic analysis reveals aberrant expression of CALR and HSPA5 in thyroid tissues of Graves' disease.
Shuai Meng,Wen Zhang,Li-juan Guan,Fatuma-Said Muhali,Jiao-zhen Zhou,Rong-hua Song,Jian Xu,Jin-an Zhang +7 more
TL;DR: In this article, a total of 34 differentially expressed proteins were observed, and the majority of these proteins were involved in endoplasmic reticulum stress (ER-stress), oxidative stress, energy metabolism, cytoskeleton and movement.
Journal ArticleDOI
Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease
Xunyao Wu,Yu Peng,Jieqiong Li,Panpan Zhang,Zheng Liu,Hui Lu,Linyi Peng,Jiaxin Zhou,Yunyun Fei,Xiaofeng Zeng,Yan Zhao,Wen Zhang +11 more
TL;DR: This study enhances the understanding of the cellular heterogeneity and transcriptional features involved in the pathogenesis of IgG4-RD, providing key clinical implications.