W
Wilfried Kuhn
Researcher at Ruhr University Bochum
Publications - 107
Citations - 8079
Wilfried Kuhn is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Parkinson's disease & Homocysteine. The author has an hindex of 34, co-authored 104 publications receiving 7711 citations.
Papers
More filters
Journal ArticleDOI
Repeat intrathecal triamcinolone acetonide application is beneficial in progressive MS patients.
V. Hoffmann,Wilfried Kuhn,Sebastian Schimrigk,S Islamova,Kerstin Hellwig,Carsten Lukas,Nils Brune,D. Pöhlau,Horst Przuntek,Thomas Müller +9 more
TL;DR: It is concluded that repeat intrathecal injection of 40 mg TCA provides a substantial benefit in progressive MS patients with predominant spinal symptoms and does not alter CSF markers of neuronal cell injury.
Journal ArticleDOI
Parenteral application of NADH in Parkinson's disease: Clinical improvement partially due to stimulation of endogenous levodopa biosynthesis
Wilfried Kuhn,Th. Müller,R. Winkel,S. Danielczik,A. Gerstner,R. Häcker,C. Mattern,Horst Przuntek +7 more
TL;DR: NADH in the used galenic form may be a potent stimulator of endogenous levodopa biosynthesis with clinical benefit for Parkinsonian patients.
Journal ArticleDOI
Homocysteine levels after acute levodopa intake in patients with Parkinson's disease.
Thomas Müller,Wilfried Kuhn +1 more
TL;DR: L‐dopa metabolism is an important component for homocysteine elevation after one time L‐dop/DDI administration in PD patients with different L‐ dopa metabolism.
Journal ArticleDOI
Therapy with central active catechol-O-methyltransferase (COMT)-inhibitors: is addition of monoamine oxidase (MAO)-inhibitors necessary to slow progress of neurodegenerative disorders?
TL;DR: It is concluded, that centrally active COMT-inhibitors may only be used together with MAO- inhibitors in the neuroprotective treatment of neurodegenerative disorders.
Book ChapterDOI
Selegiline as immunostimulant--a novel mechanism of action?
TL;DR: It is indicated that the influence of selegiline on the cytokine biosynthesis may also contribute to its putative neuroprotective properties.