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William C. Lineaweaver
Researcher at University of Mississippi Medical Center
Publications - 378
Citations - 6299
William C. Lineaweaver is an academic researcher from University of Mississippi Medical Center. The author has contributed to research in topics: Free flap & Transplantation. The author has an hindex of 37, co-authored 363 publications receiving 5723 citations. Previous affiliations of William C. Lineaweaver include University of California, Davis & Stanford University.
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Journal ArticleDOI
Studies in Flexor Tendon Wound Healing: Neutralizing Antibody to TGF-β1 Increases Postoperative Range of Motion
TL;DR: The data demonstrate that the rabbit flexor tendon repair model is useful for quantifying tendon scar formation on the basis of degrees of flexion between proximal and distal phalanges and suggest that intraoperative biochemical modulation of TGF‐&bgr;1 levels limitsflexor tendon adhesion formation.
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Cellular and bacterial toxicities of topical antimicrobials.
TL;DR: Cellular and bacterial toxicities of four commonly used topical antimicrobials were assayed in vitro using cultures of human fibroblasts and Staphylococcus aureus and fibroblast toxicity exceeded bacterial toxicity with serial dilutions of hydrogen peroxide and acetic acid.
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Gene expression of transforming growth factor beta-1 in rabbit zone II flexor tendon wound healing: evidence for dual mechanisms of repair
James Chang,Daniel Most,Eric J. Stelnicki,John W. Siebert,Michael T. Longaker,Kenneth Hui,William C. Lineaweaver +6 more
TL;DR: The findings presented here suggest that perioperative biochemical modulation of transforming growth factor beta‐1 levels may help limit flexor tendon adhesion formation.
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Effect of vascular endothelial growth factor on rat Achilles tendon healing
Feng Zhang,Hao Liu,Frank Stile,Man-Ping Lei,Yi Pang,Tanya Oswald,Joel B. Beck,Wanda Dorsett-Martin,William C. Lineaweaver +8 more
TL;DR: Administration of exogenous VEGF can significantly improve tensile strength early in the course of the rat Achilles tendon healing and was associated with increased expression of transforming growth factor-&bgr;.
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Molecular studies in flexor tendon wound healing: The role of basic fibroblast growth factor gene expression
James Chang,Daniel Most,Richard Thunder,Babak J. Mehrara,Michael T. Longaker,William C. Lineaweaver +5 more
TL;DR: It is demonstrated that normal tenocytes and tendon sheath cells are capable of bFGF production, bF GF mRNA is upregulated in the tendon wound environment, and the upregulation of this angiogenic cytokine occurs in tenocytes as well as in tendon she Heath fibroblasts and inflammatory cells.