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William R. Markesbery
Researcher at University of Louisville
Publications - 1
Citations - 600
William R. Markesbery is an academic researcher from University of Louisville. The author has contributed to research in topics: Heat shock protein & Neurodegeneration. The author has an hindex of 1, co-authored 1 publications receiving 590 citations.
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Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.
Alessandra Castegna,Michael Aksenov,Visith Thongboonkerd,Jon B. Klein,William M. Pierce,Rosemarie Booze,William R. Markesbery,D. Allan Butterfield +7 more
TL;DR: The dihydropyrimidinase related protein 2 (DRP‐2), which is involved in the axonal growth and guidance, showed significantly increased level in protein carbonyls in AD brain, suggesting a role for impaired mechanism of neural network formation in AD.