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William R. S. Barton
Researcher at Loughborough University
Publications - 5
Citations - 149
William R. S. Barton is an academic researcher from Loughborough University. The author has contributed to research in topics: Radical cyclization & Bicyclic molecule. The author has an hindex of 3, co-authored 5 publications receiving 145 citations.
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Journal ArticleDOI
Bu3SnH-mediated radical cyclisation onto azoles
Steven M. Allin,William R. S. Barton,W. Russell Bowman,Emma Bridge,Mark R. J. Elsegood,Tom McInally,Vickie McKee +6 more
TL;DR: In this article, the synthesis of bicyclic N-heterocycles using aromatic homolytic substitution was studied, in which the initiator or breakdown products from the inhibitor are responsible for the H-abstraction step.
Journal ArticleDOI
Acyl radical cyclisation onto pyrroles
TL;DR: In this article, azo radical initiators are used as oxidants of the intermediate π-radicals to generate [1,2-a]-fused pyrroles using N-(ω-acyl)-radicals generated from acylselenide precursors.
Journal ArticleDOI
Radical cyclisation onto pyrazoles: synthesis of withasomnine
TL;DR: In this paper, a novel synthetic protocol for the synthesis of [1, 2-b ]-fused bicyclic pyrazoles has been developed using radical cyclisation, which uses cyclisation of pyrazole-1-(ω-alkyl) radicals generated from 1-[phenylselenyl)alkyl]-pyrazole precursors.