scispace - formally typeset
Search or ask a question

Showing papers by "William W. Busse published in 1975"


Journal ArticleDOI
17 Mar 1975-JAMA
TL;DR: After nine months of immunotherapy with commercially prepared wholebody bee extract, a beekeeper's wife experienced anaphylaxis after a controlled bee-sting challenge and desensitization with honeybee venom was attempted.
Abstract: After nine months of immunotherapy with commercially prepared wholebody bee extract, a beekeeper's wife experienced anaphylaxis after a controlled bee-sting challenge. High risk of future bee stings prompted a decision to attempt desensitization with honeybee venom. This was extracted from the bee into Coca solution and administered parenterally in increasing daily doses until an equivalent of one venom sac was given per day. This maintenance dosage was continued for a month. Anaphylaxis did not occur after another bee-sting challenge. Therapy has been maintained with venom. With this treatment, there has been an increase in the level of IgG-blocking antibody and a fall in IgE titer to bee venom (radioallergosorbent test [RAST]). ( JAMA 231:1154-1156, 1975)

52 citations


Journal ArticleDOI
TL;DR: Symptoms of asthma developed in three patients after exposure to psyllium powder, which was being used in the manufacture of a bulk laxative, and all three had reaginic skin test sensitivity, and two had positive bronchial challenges with a psylling extract.
Abstract: Symptoms of asthma developed in three patients after exposure to psyllium powder, which was being used in the manufacture of a bulk laxative. All three had reaginic skin test sensitivity, ...

43 citations