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Xian Shen
Researcher at Wenzhou Medical College
Publications - 82
Citations - 1233
Xian Shen is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 14, co-authored 69 publications receiving 640 citations. Previous affiliations of Xian Shen include First Affiliated Hospital of Wenzhou Medical University.
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Journal ArticleDOI
Impact of different sarcopenia stages on the postoperative outcomes after radical gastrectomy for gastric cancer.
Dong-Dong Huang,Chong-Jun Zhou,Su-Lin Wang,Shu-Ting Mao,Zhou Xuanyou,Neng Lou,Zhao Zhang,Zhen Yu,Xian Shen,Cheng-Le Zhuang,Cheng-Le Zhuang +10 more
TL;DR: A large, prospective study of patients who underwent radical gastrectomy for gastric cancer from August 2014 to December 2015 found that patients had worse postoperative outcomes after Gastric cancer operation with advancing sarcopenia stages.
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Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells
Xi Chen,Ying Zhao,Wu Luo,Sian Chen,Feng Lin,Xi Zhang,Shijie Fan,Xian Shen,Yi Wang,Guang Liang +9 more
TL;DR: Inhibition of Prdx2 by Celastrol increased cellular ROS levels and led to ROS-dependent endoplasmic reticulum stress, mitochondrial dysfunction, and apoptosis in gastric cancer cells.
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Sarcopenia in overweight and obese patients is a predictive factor for postoperative complication in gastric cancer: A prospective study
Neng Lou,Chu-huai Chi,Xi-Yi Chen,Chong-Jun Zhou,Su-Lin Wang,Cheng-Le Zhuang,Cheng-Le Zhuang,Xian Shen +7 more
TL;DR: Sarcopenia is an independent predictor of postoperative complications in overweight or obese patients with gastric cancer after radical gastrectomy and figured out the impacts of sarcopenia on the postoperative complication of overweight and obese GC patients.
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Sarcopenia predicts 1-year mortality in elderly patients undergoing curative gastrectomy for gastric cancer: a prospective study.
Dong-Dong Huang,Dong-Dong Huang,Xiao-Xi Chen,Xi-Yi Chen,Su-Lin Wang,Xian Shen,Xiao-Lei Chen,Zhen Yu,Cheng-Le Zhuang,Cheng-Le Zhuang +9 more
TL;DR: Sarcopenia is predictive of 1-year mortality in elderly patients undergoing gastric cancer surgery, and the measurement of muscle function is important for sarcopenia as a preoperative assessment tool.
Journal ArticleDOI
Myosteatosis predicts prognosis after radical gastrectomy for gastric cancer: A propensity score-matched analysis from a large-scale cohort.
Cheng-Le Zhuang,Xian Shen,Yang-Yang Huang,Feng-Min Zhang,Xi-Yi Chen,Liang-Liang Ma,Xiao-Lei Chen,Zhen Yu,Su-Lin Wang +8 more
TL;DR: Classifying the skeletal muscle into subranges of radio density is a promising strategy to understand the impact of skeletal muscle on unfavorable surgical outcomes in gastric cancer patients.