http://directory.umm.ac.id/Data%20Elmu/jurnal/B/Biological%20Psichatry/Vol48.Issue8.2000/6889.pdf

Neuroimaging studies of mood disorders.

Discrete particle simulation of particulate systems: A review of major applications and findings

Statistical methods in medical research , Statistical methods in medical research , کتابخانه دیجیتال جندی شاپور اهواز

Statistical methods in medical research

Transcranial magnetic stimulation (TMS) is a technology that allows for non-invasive modulation of the excitability and function of discrete brain cortical areas TMS uses alternating magnetic fields to induce electric currents in cortical tissue In psychiatry, TMS has been studied primarily as a potential treatment for major depression Most studies indicate that slow-frequency repetitive TMS (rTMS) and higher frequency rTMS have antidepressant properties A meta-analysis of controlled studies indicates that this effect is fairly robust from a statistical viewpoint However, effect sizes are heterogeneous, and few studies have shown that rTMS results in substantial rates of clinical response or remission, and the durability of antidepressant effects is largely unknown We review in detail rTMS studies in the treatment of depression, as well as summarize treatment studies of mania, obsessive-compulsive disorder, post-traumatic stress disorder, and schizophrenia We also review the application of TMS in the study of the pathophysiology of psychiatric disorders and summarize studies of the safety of TMS in human subjects

/pdf/neuropsychiatric-applications-of-transcranial-magnetic-jei3q1qn0h.pdf

Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis.

Background Repetitive transcranial magnetic stimulation (rTMS) may be useful in the treatment of depression but results from trials have been inconclusive to date.

Aims To assess the efficacy of rTMS in treating depression.

Method We conducted a systematic review of randomised controlled trials that compared rTMS with sham in patients with depression. We assessed the quality of design of all studies and conducted a meta-analysis of data from trials with similar rTMS delivery.

Results We included a total of 14 trials. The quality of the included studies was low. Pooled analysis using the Hamilton Rating Scale for Depression showed an effect in favour of rTMS compared with sham after 2 weeks of treatment (standardised mean difference=–0.35; 95% CI –0.66 to –0.04), but this was not significant at the 2-week follow-up (standardised mean difference=-0.33; 95% CI –0.84 to 0.17).

Conclusions Current trials are of low quality and provide insufficient evidence to support the use of rTMS in the treatment of depression.

/pdf/repetitive-transcranial-magnetic-stimulation-for-the-49rzyin9sz.pdf

Repetitive transcranial magnetic stimulation for the treatment of depression. Systematic review and meta-analysis.

The stable configurations for oxygen chemisorption on the diamond (100) and (111) surfaces

The topologies of the clean and hydrogen-terminated C(100) surfaces

Changes of regional cerebral blood flow (rCBF) in five drug-resistant depressed patients were examined by single photon emission computed tomography (SPECT) with 99mTc-hexamethylpropyleneamine oxime (99mTc-HMPAO) before and after treatment with transcranial magnetic stimulation (TMS). The SPECT images were analysed with the Statistical Parametric Mapping (SPM) package. TMS administered in the region of the left dorsolateral prefrontal cortex (DLPFC) of the depressed patients was associated with an increase of rCBF at a focal region some distance from the stimulation site. No change was observed at any other remote region.

Regional cerebral blood flow changes in drug-resistant depressed patients following treatment with transcranial magnetic stimulation : a statistical parametric mapping analysis

Xiaoming Zheng

Papers

The stable configurations for oxygen chemisorption on the diamond (100) and (111) surfaces

The topologies of the clean and hydrogen-terminated C(100) surfaces

Regional cerebral blood flow changes in drug-resistant depressed patients following treatment with transcranial magnetic stimulation : a statistical parametric mapping analysis

Molecular dynamics modelling of granular chute flow: density and velocity profiles

The structure of the diamond (111) surface—a SLAB-MINDO study