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Xiaoxing Luo
Researcher at Yale University
Publications - 4
Citations - 325
Xiaoxing Luo is an academic researcher from Yale University. The author has contributed to research in topics: Pulmonary edema & Inflammation. The author has an hindex of 4, co-authored 4 publications receiving 307 citations.
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Journal ArticleDOI
Characterization of a murine model of endotoxin-induced acute lung injury.
Koroush Kabir,Jean Pierre Gelinas,Meihong Chen,Dongfen Chen,Dexin Zhang,Xiaoxing Luo,Jing-Hua Yang,Darryl Carter,Reuven Rabinovici +8 more
TL;DR: The characterization of this murine model of endotoxin-induced microvascular injury in mice will facilitate its utilization in ARDS research.
Journal ArticleDOI
Widespread inosine‐containing mRNA in lymphocytes regulated by ADAR1 in response to inflammation
Jing-Hua Yang,Xiaoxing Luo,Yongzhan Nie,Yingjun Su,Qingchuan Zhao,Koroush Kabir,Dexin Zhang,Reuven Rabinovici +7 more
TL;DR: It is reported that systemic inflammation markedly induces inosine‐containing mRNA to approximately 5% of adenosine in total mRNA, and up‐regulation of ADAR1‐mediated RNA editing is confirmed in vitro in T lymphocytes and macrophages stimulated with a variety of inflammatory mediators.
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ADAR1 Is Involved in the Development of Microvascular Lung Injury
Reuven Rabinovici,Koroush Kabir,Meihong Chen,Yingjun Su,Dexin Zhang,Xiaoxing Luo,Jing-Hua Yang +6 more
TL;DR: Data suggest that ADAR1 may play a role in the pathogenesis of microvascular lung injury possibly through induction by interferon.
Journal ArticleDOI
MOB-1 and TNF-alpha interact to induce microvascular lung injury.
TL;DR: This work provides further insight into the relationship between mob-1 and TNF-alpha in the development of lung injury assessed by pulmonary edema and leukosequestration and suggests that mob- 1 and T NF-alpha interact to promote lung inflammation.