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Xiaoyi Wei
Researcher at Peking University
Publications - 2
Citations - 13
Xiaoyi Wei is an academic researcher from Peking University. The author has contributed to research in topics: Antigen & Antibody. The author has co-authored 1 publications.
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Journal ArticleDOI
Switchable CAR-T Cells Outperformed Traditional Antibody-Redirected Therapeutics Targeting Breast Cancers
Yu Cao,Xuechun Wang,Wang Zhidong,Lijun Zhao,Shuhong Li,Zhuxia Zhang,Xiaoyi Wei,Hwayoung Yun,Sei-hyun Choi,Zhong Liu,Lili Zhao,Stephanie A. Kazane +11 more
TL;DR: In this paper, a homogeneous Her2-targeted ADC, a T cell-redirected bsAb, and a FITC-modified antibody capable of redirecting anti-FITC CAR-T (switchable CAR-Ts; sCAR-T) cells to target different Her2expressing breast cancers.
Journal ArticleDOI
A Novel Her2/VEGFR2/CD3 trispecific antibody with an optimal structural design showed improved T-cell-redirecting antitumor efficacy
Xuexiu Qi,Xiaoyi Wei,Lijun Zhao,Xuechun Wang,Shuhong Li,Zhidong Wang,Jiean Xu,Mei Hong,Zhong Liu,Lili Zhao,Xiankun Wang,B. Y. Zhang,Yuhan Zhang,Feng Wang,Yu Cao +14 more
TL;DR: In this article , a site-specific recombination strategy using various linker designs was proposed to fuse anti-Her2 (2Rs15) or anti-VEGFR2 (3VGR19) nanobodies to different positions of the anti-CD3 antibody fragment.