Xing-Wei Wong

TL;DR: Reductions in mortality were observed compared with a retrospective hyperglycaemic cohort and the SPRINT protocol achieved a high level of glycaemic control on a severely ill critical cohort population.

TL;DR: Tight control was achieved in simulation using a protocol that is easy to implement in an intensive care unit and effective in achieving and maintaining normoglycemia in critical illness.

TL;DR: There are many opportunities and unanswered questions remaining on which model-based control research can have significant clinical impact, and there is an emerging, strong need for the more rigorous analysis and methods that model- based control methods bring to this type of problem.

TL;DR: Control of blood glucose level was achieved using a protocol implemented by the nursing staff without the need for physician intervention or interpretation, where control is defined as maximizing time within a desired band.

TL;DR: Overall, tight glycemic regulation is achieved in a broad critical care cohort with optimized insulin and nutrition delivery, effectively managing glycemia even with high effective insulin resistance.