Green biosynthesis of superparamagnetic magnetite Fe3O4 nanoparticles and biomedical applications in targeted anticancer drug delivery system: A review

In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs) have been presented as a class of non-invasive nanomaterials for numerous biomedical applications. In particular, MNPs have opened a door for simultaneous diagnosis and brisk treatment of diseases in the form of theranostic agents. This review highlights the recent advances in preparation and utilization of MNPs from the synthesis and functionalization steps to the final design consideration in evading the body immune system for therapeutic and diagnostic applications with addressing the most recent examples of the literature in each section. This study provides a conceptual framework of a wide range of synthetic routes classified mainly as wet chemistry, state-of-the-art microfluidic reactors, and biogenic routes, along with the most popular coating materials to stabilize resultant MNPs. Additionally, key aspects of prolonging the half-life of MNPs via overcoming the sequential biological barriers are covered through unraveling the biophysical interactions at the bio-nano interface and giving a set of criteria to efficiently modulate MNPs' physicochemical properties. Furthermore, concepts of passive and active targeting for successful cell internalization, by respectively exploiting the unique properties of cancers and novel targeting ligands are described in detail. Finally, this study extensively covers the recent developments in magnetic drug targeting and hyperthermia as therapeutic applications of MNPs. In addition, multi-modal imaging via fusion of magnetic resonance imaging, and also innovative magnetic particle imaging with other imaging techniques for early diagnosis of diseases are extensively provided.

Synthesis, Functionalization, and Design of Magnetic Nanoparticles for Theranostic Applications

Diverse applications of nanoparticles (NPs) have revolutionized various sectors in society. In the recent decade, particularly magnetic nanoparticles (MNPs) have gained enormous interest owing to their applications in specialized areas such as medicine, cancer theranostics, biosensing, catalysis, agriculture, and the environment. Controlled surface engineering for the design of multi-functional MNPs is vital for achieving desired application. The MNPs have demonstrated great efficacy as thermoelectric materials, imaging agents, drug delivery vehicles, and biosensors. In the present review, first we have briefly discussed main synthetic methods of MNPs, followed by their characterizations and composition. Then we have discussed the potential applications of MNPs in different with representative examples. At the end, we gave an overview on the current challenges and future prospects of MNPs. This comprehensive review not only provides the mechanistic insight into the synthesis, functionalization, and application of MNPs but also outlines the limits and potential prospects.

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Review on Recent Progress in Magnetic Nanoparticles: Synthesis, Characterization, and Diverse Applications

Magnetic nanomaterials show promising applications in heterogeneous catalysis because of their ease of separation and good reusability. The magnetization saturation values of magnetic nanoparticles...

Applications of Magnetic Nanomaterials in Heterogeneous Catalysis

The effect of particle shape on cellular interaction and drug delivery applications of micro- and nanoparticles.

Facile co-precipitation synthesis of shape-controlled magnetite nanoparticles

The invention relates to an asymmetric hydrogenation catalyst In order to provide a reusable and environmental-friendly asymmetric hydrogenation catalyst with high stability and high enantioselectivity, the asymmetric hydrogenation catalyst of the Ru-base complex of the invention is a Ru-base loaded composite material prepared from a Ru-Salen complex by taking a mesoporous material SBA-16 as a carrier, wherein the Ru-Salen complex is prepared by taking RuCl2 (PPh3)3 as a catalyst precursor and different chiral Salens as ligands, and the Ru-base loaded composite material is prepared by an in-bottle ship construction method or a direct encapsulation method By the asymmetric hydrogenation catalyst, the Ru-Salen complex is loaded into a supercage made of the mesoporous material SBA-16 in different ways, a novel composite catalyst is provided for the polyphase production of chiral medicaments, and the application of the mesoporous material to industrial production is expanded

Asymmetric hydrogenation catalyst of Ru-base complex

The invention relates to a ferroferric oxide/polypyrrole composite material, which comprises ferroferric oxide and polypyrrole, wherein particle size distribution of Fe3O4 particles in the ferroferric oxide/polypyrrole composite material is 5-30 nm, saturation magnetization of the ferroferric oxide/polypyrrole composite material is 30-70 emu/g, and electrical conductivity is 5-20 S/cm. The preparation method has advantages of simple operation and low cost.

Ferroferric oxide/polypyrrole composite material and preparation method thereof

The present invention discloses a recycling method of ethylene oxide-containing organic waste gas. The specific technical scheme comprises that: ethylene oxide in ethylene oxide-containing organic waste gas is subjected to circulation absorbing in a hydrolysis tower by using dilute sulfuric acid with a certain concentration as an absorbent so as to produce a hydration reaction to generate ethylene glycol, the ethylene glycol is conveyed into an ethylene glycol solution storage tank after the ethylene glycol in the solution achieves a certain concentration, a sodium hydroxide solution is added to neutralize, one part of the neutralized ethylene glycol solution is used for the acid gas washing process, the other part is conveyed to the product separation and recovery, the tail gas discharged from the hydrolysis tower enters a reactor to carry out deep oxidation, an acid gas washing treatment is performed, the treated standard tail gas is discharged into the atmosphere, and the absorbing liquid is recycled to the ethylene glycol solution storage tank. According to the present invention, the method has characteristics of short process and simple operation, and with the treatment of the present invention, the ethylene oxide content in the organic waste gas tail gas does not exceed 1 ppm, and a certain amount of the ethylene glycol solution is recovered so as to achieve the resource utilization of the waste gas.

Yang Guochen

Papers

Facile co-precipitation synthesis of shape-controlled magnetite nanoparticles

Asymmetric hydrogenation catalyst of Ru-base complex

Ferroferric oxide/polypyrrole composite material and preparation method thereof

Recycling method of ethylene oxide-containing organic waste gas

Preparation method of mitiglinide calcium