Y
Yanpeng Wang
Researcher at Shanghai Jiao Tong University
Publications - 5
Citations - 279
Yanpeng Wang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Apoptosis & Reactive oxygen species. The author has an hindex of 2, co-authored 3 publications receiving 236 citations. Previous affiliations of Yanpeng Wang include University of Western Ontario & Lawson Health Research Institute.
Papers
More filters
Journal ArticleDOI
MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1
Huaqing Zhu,Yixin Yang,Yixin Yang,Yanpeng Wang,Yanpeng Wang,Yanpeng Wang,Jianmin Li,Peter W. Schiller,Tianqing Peng,Tianqing Peng +9 more
TL;DR: A pro-apoptotic role of miR-195 in cardiomyocytes is demonstrated and Sirt1 is identified as a direct target of mi R-195 and may be a new therapeutic target for lipotoxicCardiomyopathy.
Journal ArticleDOI
Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways
Jian Ma,Yanpeng Wang,Yanpeng Wang,Yanpeng Wang,Dong Zheng,Meng Wei,Huaxi Xu,Tianqing Peng,Tianqing Peng +8 more
TL;DR: In a mouse model of acute doxorubicin-induced cardiotoxicity, cardiomyocyte-specific deletion of Rac1 inhibited NADPH oxidase activation and ROS production, prevented cardiac cell death, and improved myocardial function in Rac1 knockout mice and therapeutic administration of the specific Rac1 inhibitor NSC23766 achieved similar cardio-protective effects.
Journal ArticleDOI
Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species dependent and independent pathways
TL;DR: In a mouse model of acute doxorubicin-induced cardiotoxicity, cardiomyocyte-specific deletion of Rac1 inhibited NADPH oxidase activation and ROS production, prevented cardiac cell death and improved myocardial function in Rac1 knockout mice, suggesting inhibition of Rac 1 may be a useful therapy for dox orubic in-inducedCardiotoxicity.
Journal ArticleDOI
Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway
Ming Lu,Yanpeng Wang,Yuanye Jiang,Cuiping Zhang,Hongping Wang,Wenjun Sha,Lin Chen,Tao Lei,Limei Liu +8 more
Journal ArticleDOI
Corrigendum to “Generation of a human Charcot-Marie-Tooth disease type 1B (CMT1B) iPSC line, ZJUCHi001-A, with a mutation of c.292C>T in MPZ” [Stem Cell Res. 35C (2019) 101407]
Jiake Xu,Yanpeng Wang,Jing He,Weichun Xia,Yuan Zou,Wen-wei Ruan,Ying Eileen Li,Haifeng Li,Wei Chen +8 more