An xanthone compound substituted by 2,4-difluorophenyl is disclosed The compound is 7-(2,4-difluorophenyl)-1,3-dihydroxyl xanthone The structure of the compound is shown as a following formula The7-(2,4-difluorophenyl)-1,3-dihydroxyl xanthone is a novel xanthone compound, has obvious antitumor activity and tyrosinase inhibiting activity, and can be used for preparing antitumor medicines, and medicines, healthcare products, foods and cosmetics in the field of tyrosinase regulation A preparing method of the xanthone compound is simple to operate, reaction conditions are mild, the yield is high and the method can be used for large-scale preparation of the 7-(2,4-difluorophenyl)-1,3-dihydroxyl xanthone

An xanthone compound substituted by 2,4-difluorophenyl, a preparing method thereof and applications of the compound

The invention discloses a trifluoromethyl substituted xanthone compound which is 6-trifluoromethyl-1,3-dyhydroxyl xanthone. The structure of the compound is as shown in the specification. The 6-trifluoromethyl-1,3-dyhydroxyl xanthone is a novel xanthone compound, has obvious antitumor activity and tyrosinase activity inhibition, and can be used for preparing antitumor drugs and tyrosinase metabolic regulation drugs, health care products, food and cosmetics. The preparation method of 6-trifluoromethyl-1,3-dyhydroxyl xanthone provided by the invention is simple in operation, mild in reaction conditions and high in yield, and can be used for larges-scale preparation of 6-trifluoromethyl-1,3-dyhydroxyl xanthone.

Trifluoromethyl substituted xanthone compound and preparation method and application thereof

The invention discloses application of a xanthone compound CCE9. The xanthone compound CCE9 is used for preparing a drug for treating cancer. By activating p38MAPK, Bcl-2 is phosphorylated, the conformation of Bcl-2 is changed, and Bax is activated, so that sub tumor cell apoptosis is induced. Therefore, the xanthone compound CCE9 can be used for preparing a drug taking Bcl-2 as an action target spot for treating cancer. In addition, Bcl-2 which is phosphorylated can be used as the action target spot for screening the xanthone compound.

Yao Xinsheng

Papers

Application of xanthone compound CCE9