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Yayoi Nishiyama
Researcher at Teikyo University
Publications - 60
Citations - 2188
Yayoi Nishiyama is an academic researcher from Teikyo University. The author has contributed to research in topics: Candida albicans & Essential oil. The author has an hindex of 21, co-authored 59 publications receiving 1813 citations.
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Journal ArticleDOI
Proliferation of Intracellular Structure Corresponding to Reduced Affinity of Fluconazole for Cytochrome P‐450 in Two Low‐Susceptibility Strains of Candida albicans Isolated from a Japanese AIDS Patient
Kazunori Maebashi,Michinari Kudoh,Yayoi Nishiyama,Koichi Makimura,Yasuki Kamai,Katsuhisa Uchida,Hideyo Yamaguchi +6 more
TL;DR: Characteristics related to cytochrome P‐450 (CYP), especially sterol 14α‐demethylase encoded by the ERG11 gene which is the target molecule for fluconazole, are examined, finding the development of mesh membrane structures of the endoplasmic reticula, which is a location related to sterol synthesis, was the most prominent finding.
Journal Article
A Queensland koala kept in a Japanese zoological park was carrier of an imported fungal pathogen, Filobasidiella neoformans var. bacillispora (Cryptococcus neoformans var. gattii).
Koichi Makimura,Mizuki Karasawa,Humio Hosoi,Toshiki Kobayashi,Nanako Kamijo,Kazuhiro Kobayashi,Hiroshi Hiramatsu,Takako Akikawa,Tomoko Yabe,Ayumi Yamaguchi,Ishida Osamu,Arisa Murakami,Ryuichi Fujisaki,Yayoi Nishiyama,Katsuhisa Uchida,Hideyo Yamaguchi +15 more
TL;DR: Yeasts were isolated as pure cultures from nose discharge and autopsy materials (brain, nasal cavity, and lung), and diagnosed as Cryptococcus neoform?ns on the basis of the characteristic thick capsules.
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Oral administration of itraconazole solution has superior efficacy in experimental oral and oesophageal candidiasis in mice than its intragastric administration
TL;DR: Oral administration of itraconazole OS displayed therapeutic efficacy against murine oral and oesophageal candidiasis superior to that achieved by intragastric administration.
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Effect of cinnamaldehyde on hyphal growth of C. albicans under various treatment conditions.
TL;DR: Findings suggest that a warm drink or mouthwash containing cinnamaldehyde might be a candidate as a prophylactic or therapeutic tool against oral Candida infection.
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Ultrastructural alterations of Candida albicans induced by a new imidazole antimycotic omoconazole nitrate.
TL;DR: The cytological alteration induced by exposure to a higher concentration (40 μg/ml) of the drug was characterized by disruption of the intracytoplasmic organelles, confirming the strong antifungal activity of OMZ against fungal cells.