Ye Cheng

TL;DR: This study summarizes discoveries achieved recently in terms of the principles of sorafenib resistance and outlines approaches suitable for improving therapeutic outcomes for HCC patients.

TL;DR: In this article, the main tumor animal models and the application progress of animal models in tumor research are systematically reviewed and combined with the latest progress and development trend in this field, the future research of tumor animal model was prospected.

TL;DR: This study focuses on non-coding RNAs (ncRNAs) to summarize the epigenetic consequences of RNA modifications, and the pathogenesis of cancer, as diagnostic markers and therapeutic targets forcancer, as well as the mechanisms affecting the immune environment of cancer.

TL;DR: There is growing evidence that piRNAs and PIWI proteins are abnormally expressed in various types of cancers, which may be potential cancer biomarkers and cancer therapeutic targets.

TL;DR: In this paper, the authors review the FDA-approved use of small molecule targeted compounds in tumors, summarize the clinical drug resistance problems and mechanisms facing the use of Small-Miner targeted compounds, and predict the future directions of the evolving field.