Yi-Xian Qin

TL;DR: Mechanical targeting of the bone marrow stem-cell pool might represent a novel, drug-free means of slowing the age-related decline of the musculoskeletal system.

TL;DR: That these deformations are several orders of magnitude below those peak strains which arise during vigorous activity indicates that this biomechanically based signal may serve as an effective intervention for osteoporosis.

TL;DR: Results show that variable damping coefficients and the asymmetric feature in jounce and rebound motions are achieved by controlling the electrical load of the shock absorber.

TL;DR: In general, the inorganic nanoparticle MSNP showed a better or equivalent mechanical reinforcement compared to carbon nanomaterials, and 2D nanostructures (GONPs, MSNPs) are better reinforcing agents compared to one-dimensional (1D) nanostructureures (e.g., SWCNTs).

TL;DR: The results confirm the strong antiresorptive influence of mechanical loading and identify a threshold near 70 microstrain for a daily loading cycle regimen of approximately 100,000 strain cycles, suggesting that the frequency or strain rate associated with the loading stimulus must also play a critical role in the mechanism by which bone responds to mechanical strain.