Y
Yin Yani
Researcher at Agency for Science, Technology and Research
Publications - 7
Citations - 235
Yin Yani is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Crystal & Hildebrand solubility parameter. The author has an hindex of 7, co-authored 7 publications receiving 177 citations.
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Molecular simulation study of the effect of various additives on salbutamol sulfate crystal habit.
TL;DR: The results suggest that PVP is the most effective among the three additives for the inhibition of SS crystal growth, and could be a powerful tool for selection of habit-modifying additives in other crystallization systems.
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Glycine Open Dimers in Solution: New Insights into α-Glycine Nucleation and Growth
TL;DR: In this article, the authors investigated the clustering behavior of glycine molecules in supersaturated aqueous solutions using molecular dynamics (MD) simulation, and they found that there are always at least 12% of GMs existing as open dimers.
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Effect of API-Polymer Miscibility and Interaction on the Stabilization of Amorphous Solid Dispersion: A Molecular Simulation Study
TL;DR: In this paper, a molecular dynamics simulation technique was employed to predict miscibility and interaction of Active Pharmaceutical Ingredient (API) with polymer carriers in solid dispersion system based on Hansen solubility parameter and hydrogen bond formation, respectively.
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Anisotropic Crystal Growth Inhibition by Polymeric Additives: Impact on Modulation of Naproxen Crystal Shape and Size
Sendhil K. Poornachary,Vernissa Dilys Chia,Yin Yani,Guangjun Han,Pui Shan Chow,Reginald B. H. Tan,Reginald B. H. Tan +6 more
TL;DR: In this article, the effects of polymeric additives such as hydroxypropyl methyl cellulose (HPMC) and polyvinylpyrrolidone (PVP) on the growth kinetics of naproxen crystal were investigated.
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Orally Disintegrating Tablets Containing Melt Extruded Amorphous Solid Dispersion of Tacrolimus for Dissolution Enhancement
Poovizhi Ponnammal,Parijat Kanaujia,Yin Yani,Wai Kiong Ng,Wai Kiong Ng,Reginald B. H. Tan,Reginald B. H. Tan +6 more
TL;DR: The extrudates were found to be stable under accelerated storage conditions for 3 months with no re-crystallization, indicating that hot melt extrusion is suitable for producing stable amorphous solid dispersions of TAC in PVP VA64, Soluplus® and HPC.