Essential oils for the development of eco-friendly mosquito larvicides: A review

This review aims to describe essential oils and their constituent compounds that exhibit bioactivity against Aedes aegypti L (Diptera: Culicidae) larvae, the immature stage of the primary vector of dengue This review is based on original articles obtained by searching on major databases Our literature review revealed that 361 essential oils from 269 plant species have been tested for their larvicidal activity More than 60 % of these essential oils were considered active (LC50<100 mg/L), and the majority of these active oils were derived from species belonging to Myrtaceae, Lamiaceae, and Rutaceae The most active essential oils exhibited effective concentrations comparable with the dosage recommended for the use of temephos in container breeding Approximately 27 % of the plants studied for their larvicidal activity against A aegypti were collected in Brazil Essential oils rich in phenylpropanoids, oxygenated sesquiterpenes, and monoterpene hydrocarbons were found to be the most active When the isolates were tested, phenylpropanoids and monoterpene hydrocarbons were the most active compound classes We describe the plant parts used and the major constituents of the essential oils In addition, we discuss factors affecting the activity (such as plant parts, age of the plant, chemotypes, larval source, and methods used), structure-activity relationships, and mechanisms of action of the essential oils and their compounds Essential oils have been widely investigated and show high larvicidal activity against A aegypti This review reveals that the essential oils are effective alternatives for the production of larvicides, which can be used in vector-borne disease control programmes

Essential oils and their compounds as Aedes aegypti L. (Diptera: Culicidae) larvicides: review

The genus Eucalyptus L'Heritier comprises about 900 species, of which more than 300 species contain volatile essential oil in their leaves. About 20 species, within these, have a high content of 1,8-cineole (more than 70%), commercially used for the production of essential oils in the pharmaceutical and cosmetic industries. However, Eucalyptus is extensively planted for pulp, plywood and solid wood production, but its leaf aromatic oil has astounding widespread biological activities, including antimicrobial, antiseptic, antioxidant, chemotherapeutic, respiratory and gastrointestinal disorder treatment, wound healing, and insecticidal/insect repellent, herbicidal, acaricidal, nematicidal, and perfumes, soap making and grease remover. In the present review, we have made an attempt to congregate the biological ingredients of leaf essential oil, leaf oil as a natural medicine, and pharmacological and toxicological values of the leaf oil of different Eucalyptus species worldwide. © 2017 Society of Chemical Industry.

Biological, Medicinal and Toxicological Significance of Eucalyptus Leaf Essential Oil: A Review

This research highlights the chemical composition, antioxidant, anti-inflammatory and anti-proliferative activities of essential oils from leaves of Ocimum basilicum, Ocimum americanum, Hyptis spicigera, Lippia multiflora, Ageratum conyzoides, Eucalyptus camaldulensis and Zingiber officinale. Essential oils were analyzed by gas chromatography–mass spectrometry and gas chromatography–flame ionization detector. Major constituents were α-terpineol (59.78%) and β-caryophyllene (10.54%) for Ocimum basilicum; 1, 8-cineol (31.22%), camphor (12.730%), α-pinene (6.87%) and trans α-bergamotene (5.32%) for Ocimum americanum; β-caryophyllene (21%), α-pinene (20.11%), sabinene (10.26%), β-pinene (9.22%) and α-phellandrene (7.03%) for Hyptis spicigera; p-cymene (25.27%), β-caryophyllene (12.70%), thymol (11.88), γ-terpinene (9.17%) and thymyle acetate (7.64%) for Lippia multiflora; precocene (82.10%)for Ageratum conyzoides; eucalyptol (59.55%), α-pinene (9.17%) and limonene (8.76%) for Eucalyptus camaldulensis; arcurcumene (16.67%), camphene (12.70%), zingiberene (8.40%), β-bisabolene (7.83%) and β-sesquiphellandrene (5.34%) for Zingiber officinale. Antioxidant activities were examined using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) methods. O. basilicum and L. multiflora exhibited the highest antioxidant activity in DPPH and ABTS tests, respectively. Anti-inflammatory properties were evaluated by measuring the inhibition of lipoxygenase activity and essential oil of Z. officinale was the most active. Anti-proliferative effect was assayed by the measurement of MTT on LNCaP and PC-3 prostate cancer cell lines, and SF-763 and SF-767 glioblastoma cell lines. Essential oils from A. conyzoides and L. multiflora were the most active on LNCaP and PC-3 cell lines, respectively. The SF-767 glioblastoma cell line was the most sensitive to O. basilicum and L. multiflora EOs while essential oil of A. conyzoides showed the highest activity on SF-763 cells. Altogether these results justify the use of these plants in traditional medicine in Burkina Faso and open a new field of investigation in the characterization of the molecules involved in anti-proliferative processes.

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Chemical Composition, Antioxidant, Anti-Inflammatory and Anti-Proliferative Activities of Essential Oils of Plants from Burkina Faso

https://www.alice.cnptia.embrapa.br/bitstream/doc/882539/1/PA10006.pdf

Chemical composition of Eucalyptus spp. essential oils and their insecticidal effects on Lutzomyia longipalpis

Chemical compositions and larvicidal activities of leaf essential oils from two eucalyptus species

In this study, solid-phase micro-extraction (SPME) fibers coated with polydimethylsiloxane/divinylbenzene (PDMS/DVB), coupled with gas chromatography/mass spectrometry, were used to monitor the emission patterns of biogenic volatile organic compounds (BVOCs) from leaves of Calocedrus macrolepis var. formosana Florin. in situ. In both sunny and rainy weather, the circadian profile for BVOCs from C. macrolepis var. formosana leaves has three maximum emission cycles each day. This kind of emission pattern might result from the plant’s circadian clock, which determines the rhythm of terpenoid emission. Furthermore, emission results from the leaves demonstrated that the circadian profile of α-pinene observed was opposite to the profiles of limonene and myrcene, a difference that may be attributable to two different subpathways for terpenoid biosynthesis.

https://link.springer.com/content/pdf/10.1007%2Fs10086-009-1071-z.pdf

Monitoring the emission of volatile organic compounds from the leaves of Calocedrus macrolepis var. formosana using solid-phase micro-extraction

Three Chamaecyparis species (C. formosensis, C. obtusa, and C. obtusa var. formosana) are difficult to distinguish by the naked eye. Therefore, from the chemotaxonomic point of view, it would be valuable to find a simple and rapid method to differentiate these three Chamaecyparis species. In this study, the chemical compositions of biogenic volatile organic compounds (BVOCs) from mature leaves were analyzed using solid-phase microextraction-gas chromatography/mass spectrometry (SPME-GC/MS). Then cluster analysis (CA) and principal component analysis (PCA) were conducted for the BVOC constituents to reveal the differences among these three species. Results from SPME-GC/MS showed that the compositions of BVOCs from the three species were distinctly different. Moreover, these species were clearly differentiated according to the results of CA and PCA. In conclusion, the findings of this study suggest that SPME-GC/MS coupled with CA and PCA is a feasible and rapid technique to differentiate Chamaecyparis species with similar morphological characteristics.

Rapid differentiation of three Chamaecyparis species (Cupressaceae) grown in Taiwan using solid-phase microextraction-gas chromatography/mass spectrometry, cluster analysis, and principal component analysis.

Cinnamomum kanehirae Hayata is an endemic tree species in Taiwan. Leaf essential oils from 26 sources of C. kanehirae were obtained by hydrodistillation and their chemical constituents were analyzed by gas chromatography-mass spectrometry (GC-MS). Fifty-eight compounds were identified from C. kanehirae leaf essential oils. The main constituents in leaf essential oils were linalool, 1,8-cineole, β-selinene, 1-hexadecyne, and α-cadinol. According to the chemical compositions of leaf essential oils and their relative contents obtained from GC-MS analyses, cluster analysis, and principal component analysis, the 26 sources examined were classified into five chemotypes: linalool type, linalool/1,8-cineole type, 1,8-cineole type, linalool/α-cadinol type, and mixed type. The biochemical correlations between the major constituents of C. kanehirae were examined and their relationship is discussed.

Chemical Polymorphism and Composition of Leaf Essential Oils of Cinnamomum kanehirae Using Gas Chromatography/Mass Spectrometry, Cluster Analysis, and Principal Component Analysis

In this study, inhibitory activities of leaf essential oils from Cinnamomum osmophloeum and Cinnamomum zeylanicum and their major constituents (trans-cinnamaldehyde and eugenol) against Rhizoctonia solani were investigated. Furthermore, the relationship between the antipathogenic activity and the chemical structure of trans-cinnamaldehyde and eugenol is discussed. Results demonstrated that leaf essential oils and their major constituents from C. osmophloeum and C. zeylanicum had strong antipathogenic activities against R. solani. Results obtained from the chemical structure–antipathogenic activity relationship study suggested that trans-cinnamaldehyde or (E)-cinnamic acid with an aldehyde (‒CHO) or an acid (‒COOH) group, a conjugated double bond, and a Length of CH chain outside the ring affect their antipathogenic activity. Furthermore, the presence of the methyl moiety in the ortho position may have a considerable influence on the inhibitory action against R. solani. In addition, compounds with...

Ying-Ju Chen

Papers

Chemical compositions and larvicidal activities of leaf essential oils from two eucalyptus species

Monitoring the emission of volatile organic compounds from the leaves of Calocedrus macrolepis var. formosana using solid-phase micro-extraction

Rapid differentiation of three Chamaecyparis species (Cupressaceae) grown in Taiwan using solid-phase microextraction-gas chromatography/mass spectrometry, cluster analysis, and principal component analysis.

Chemical Polymorphism and Composition of Leaf Essential Oils of Cinnamomum kanehirae Using Gas Chromatography/Mass Spectrometry, Cluster Analysis, and Principal Component Analysis

Antipathogenic Activities and Chemical Composition of Cinnamomum osmophloeum and Cinnamomum zeylanicum Leaf Essential Oils