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Ying Yue
Researcher at Jilin University
Publications - 1
Citations - 39
Ying Yue is an academic researcher from Jilin University. The author has contributed to research in topics: Warburg effect & Apoptosis. The author has an hindex of 1, co-authored 1 publications receiving 28 citations.
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Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells.
Wenjia Zhang,Jing Su,Huadan Xu,Shanshan Yu,Yanan Liu,Yong Zhang,Liankun Sun,Ying Yue,Xiaoli Zhou +8 more
TL;DR: DIC potently inhibited the kinase activity of PDK1, shifted the glucose metabolism from aerobic glycolysis to oxidative phosphorylation, generated a higher level of reactive oxygen species (ROS), attenuated the mitochondrial membrane potential (MMP), induced apoptosis, and reduced cell viability in vitro.