Y
Yisheng He
Researcher at Howard Hughes Medical Institute
Publications - 16
Citations - 631
Yisheng He is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Neuroblast & Neuron. The author has an hindex of 8, co-authored 11 publications receiving 479 citations. Previous affiliations of Yisheng He include University of Massachusetts Amherst & University of Massachusetts Medical School.
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Journal ArticleDOI
Clonal Development and Organization of the Adult Drosophila Central Brain
Hung-Hsiang Yu,Takeshi Awasaki,Mark David Schroeder,Fuhui Long,Jacob S. Yang,Yisheng He,Peng Ding,Jui-Chun Kao,Gloria Yueh-Yi Wu,Hanchuan Peng,Gene Myers,Tzumin Lee,Tzumin Lee +12 more
TL;DR: By determining individual NB clones and pursuing their projections into specific neuropils, this work unravels the regional development of the brain neural network in Drosophila central brain.
Journal ArticleDOI
A Complete Developmental Sequence of a Drosophila Neuronal Lineage as Revealed by Twin-Spot MARCM
TL;DR: Labeling every neuron in a lineage in the fruit fly olfactory system reveals that every cell is born with a pre-determined cell fate that is invariant and dependent upon neuron birth order.
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Stem Cell-Intrinsic, Seven-up-Triggered Temporal Factor Gradients Diversify Intermediate Neural Progenitors
Qingzhong Ren,Ching-Po Yang,Zhiyong Liu,Ken Sugino,Kent Mok,Yisheng He,Masayoshi Ito,Aljoscha Nern,Hideo Otsuna,Tzumin Lee +9 more
TL;DR: It is proposed that the Seven-up-initiated Imp/Syp gradients create coarse temporal windows within type II neuroblasts to pattern INPs, which subsequently undergo fine-tuned subtemporal patterning.
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Making Drosophila lineage–restricted drivers via patterned recombination in neuroblasts
Takeshi Awasaki,Takeshi Awasaki,Chih-Fei Kao,Chih-Fei Kao,Ying Jou Lee,Ching Po Yang,Yaling Huang,Barret D. Pfeiffer,Haojiang Luan,Xiaotang Jing,Yu-Fen Huang,Yisheng He,Mark David Schroeder,Alexander Kuzin,Thomas Brody,Christopher T. Zugates,Ward F. Odenwald,Tzumin Lee,Tzumin Lee +18 more
TL;DR: New genetic tools that target neuroblasts and their diverse descendants are developed, increasing the ability to study fly brain structure and development and converting conventional drivers that are temporarily expressed in neuroblast, into drivers expressed in all subsequent neuroblast progeny.
Journal ArticleDOI
Diverse neuronal lineages make stereotyped contributions to the Drosophila locomotor control center, the central complex.
Jacob S. Yang,Takeshi Awasaki,Hung-Hsiang Yu,Yisheng He,Peng Ding,Jui-Chun Kao,Tzumin Lee,Tzumin Lee +7 more
TL;DR: 15 distinct clones that carry larval‐born neurons innervating the Drosophila central complex (CX), which consists of four midline structures including the protocerebral bridge, fan‐shaped body (FB), ellipsoid body (EB), and noduli (NO), are identified.