Yiting Qiao

TL;DR: This review offers a comprehensive overview of several specific stimuli, including internal stimuli and external stimuli, and envision that applications of these smart nanotherapeutics can benefit cancer patients and provide a good chance for clinical translation of many nanoparticle formulas.

TL;DR: The extracellular matrix (ECM) is one of the major components of tumors that plays multiple crucial roles, including mechanical support, modulation of the microenvironment, and a source of signaling molecules as discussed by the authors.

TL;DR: Injection of nanoparticles containing the anticancer drug gefitinib and the immunosuppressant cyclosporin A reverses drug-resistant cancer growth in mice and provides an alternative administration route for the drugs of choice but also effectively reverses MDR, facilitating the development of effective therapeutic modalities for cancer.

TL;DR: Findings indicate that Salmonella‐mediated tumor‐targeted therapy with TRAIL could reduce tumor growth and extend host survival and that VNP20009 expressing TRAIL yielded its antitumor effect by inducing melanoma apoptosis.

TL;DR: It is revealed that triptolide could significantly enhance the antitumour effect of VNP20009 by modulating tumour angiogenesis and the host immune response, providing a new understanding of the strategy to improve Salmonella-mediated tumour therapy.