Y
Yong Chen
Publications - 2
Citations - 149
Yong Chen is an academic researcher. The author has contributed to research in topics: Gene silencing & Small hairpin RNA. The author has an hindex of 2, co-authored 2 publications receiving 146 citations.
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Journal ArticleDOI
RNAi for Treating Hepatitis B Viral Infection
TL;DR: Several strategies for improving the anti-HBV therapeutic efficacy of siRNAs, while avoiding their off-target effects and immunostimulation are discussed.
Journal ArticleDOI
siRNA pool targeting different sites of human hepatitis B surface antigen efficiently inhibits HBV infection
Yong Chen,Ram I. Mahato +1 more
TL;DR: A pool of chemically synthesised siRNAs as well as the shRNA expression plasmid encoding multiple shRNAs targeting different regions of HBsAg showed high gene silencing in HepG2.2.15 cells, suggesting no induction of IFN response.