Y
Yongfeng Wang
Researcher at Peking University
Publications - 12
Citations - 527
Yongfeng Wang is an academic researcher from Peking University. The author has contributed to research in topics: Neuroblastoma & Signal transduction. The author has an hindex of 10, co-authored 11 publications receiving 461 citations. Previous affiliations of Yongfeng Wang include Baylor College of Medicine.
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Journal ArticleDOI
Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinoma†
Qing Xie,Xiangmei Chen,Fengmin Lu,Ting Zhang,Meili Hao,Meili Hao,Yongfeng Wang,Jingmin Zhao,Malcolm A. McCrae,Hui Zhuang +9 more
TL;DR: The authors investigated the tumorigenic mechanism of this oncomir in the development of HCC and suggested that it is up‐regulated in hepatocellular carcinoma.
Journal ArticleDOI
Re-evaluation of the Carcinogenic Significance of Hepatitis B Virus Integration in Hepatocarcinogenesis
Suzhen Jiang,Suzhen Jiang,Ziwei Yang,Weijie Li,Xiaojun Li,Yongfeng Wang,Jiangbo Zhang,Chunhui Xu,Pei-Jer Chen,Jinlin Hou,Malcolm A. McCrae,Xiangmei Chen,Hui Zhuang,Fengmin Lu +13 more
TL;DR: The frequency and patterns ofHBV insertions were similar between tumor and their adjacent non-tumor samples indicating that the majority of HBV DNA integration events are not associated with hepatocarcinogenesis.
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Methylation‐mediated repression of microRNA 129‐2 enhances oncogenic SOX4 expression in HCC
Xiangmei Chen,Ling Zhang,Ting Zhang,Meili Hao,Xiaolei Zhang,Jiangbo Zhang,Qing Xie,Yongfeng Wang,Mingzhou Guo,Hui Zhuang,Fengmin Lu +10 more
TL;DR: The involvement of miR‐129‐2 in HBV infection‐related HCC is investigated and it is found that this molecule is involved in hepatocarcinogenesis through pathways related to EMT and ‘cell reprograming’.
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Comprehensive profiling of novel microRNA-9 targets and a tumor suppressor role of microRNA-9 via targeting IGF2BP1 in hepatocellular carcinoma
Jiangbo Zhang,Jin Cheng,Zhenzhen Zeng,Yongfeng Wang,Xiaojun Li,Qing Xie,Junqiao Jia,Ying Yan,Zhengyang Guo,Jian Gao,Mingjie Yao,Xiangmei Chen,Fengmin Lu +12 more
TL;DR: This study suggests that miR-9 functions as a tumor suppressor in HCC progression by inhibiting a series of target genes, including the newly validated miR -9/IGF2BP1/AKT&ERK axis, thus providing potential therapeutic targets and novel prognostic biomarkers for HCC patients.
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Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma
Yongfeng Wang,Jin Cheng,Chunhui Xu,Shuang Liu,Suzhen Jiang,Qiang Xu,Xiangmei Chen,Hui Zhuang,Fengmin Lu +8 more
TL;DR: Frequent promoter hypermethylation of the inhibitors in either Rb or p53 pathways is associated with the hepatocellular carcinoma (HCC) development.