Yoshimasa Machida

TL;DR: In this article, a very mild and extremely efficient method for the dealkylation of 1 containing labile functional groups was presented, which is the only known method for this purpose, albeit mild, taking several days and the yields are not always satisfactory.

TL;DR: A biphenyl derivative represented by the following formula (I) or a pharmacologically acceptable salt thereof is clinically useful for treating and ameliorating mental disorders such as cerebrovascular disorder, aggressive behavior due to senile dementia, mental excitation, poriomania, delirium, hallucination, hyperkinesia, schizophrenia, emotional disturbance, depression, neurosis, psychophysiologic disorder and anxiety neurosis as discussed by the authors.

TL;DR: A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases.

TL;DR: A 3-propenylcephem derivative of the following formula: as mentioned in this paper, where R 1 represents a fluoro-substituted lower alkyl group and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof.

TL;DR: In this paper, a compound represented by the formula: wherein R, is hydrogen or methoxy; R2 is hydrogen, or hydroxy; R is wherein R3 and R4 are hydroxy or acyloxy, Y is oxygen, sulfur, or N-R5 wherein R5 is hydrogen lower alkyl, and Z is sulfur or N -R5 where R5 has the same meanings as defined above; and X is where R6 is acylox or nitrogen-containing hetero-cyclicthio which may have substituent(s),