Y
Young Mi Kim
Researcher at Pusan National University
Publications - 146
Citations - 2262
Young Mi Kim is an academic researcher from Pusan National University. The author has contributed to research in topics: Prodrug & Aminosalicylic acid. The author has an hindex of 24, co-authored 136 publications receiving 2053 citations.
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Journal ArticleDOI
Sphingosylphosphorylcholine induces differentiation of human mesenchymal stem cells into smooth-muscle-like cells through a TGF-β-dependent mechanism
Eun Su Jeon,Hyun Jung Moon,Mi Jeong Lee,Hae Young Song,Young Mi Kim,Yong Chan Bae,Jin Sup Jung,Jae Ho Kim +7 more
TL;DR: SPC induces differentiation of human adipose-tissue-derived mesenchymal stem cells to smooth-muscle-like cell types through Gi/o-ERK-dependent autocrine secretion of TGF-β, which activates a Smad2-SRF/myocardin-dependent pathway.
Journal ArticleDOI
Cancer‐Derived Lysophosphatidic Acid Stimulates Differentiation of Human Mesenchymal Stem Cells to Myofibroblast‐Like Cells
Eun Su Jeon,Hyun Jung Moon,Mi Jeong Lee,Hae Young Song,Young Mi Kim,Mong Cho,Dong-Soo Suh,Man-Soo Yoon,Chulhun L. Chang,Jin Sup Jung,Jae Ho Kim +10 more
TL;DR: It is suggested that cancer‐derived LPA stimulates differentiation of hADSCs to myofibroblast‐like cells and increases SDF‐1 expression through activating autocrine TGF‐β1‐Smad signaling pathway.
Journal ArticleDOI
Metabolic and Pharmacological Properties of Rutin, a Dietary Quercetin Glycoside, for Treatment of Inflammatory Bowel Disease
Heejung Kim,Hyesik Kong,Boim Choi,Youngwook Yang,Young Mi Kim,Mi Jung Lim,Len Neckers,Yunjin Jung +7 more
TL;DR: The data suggest that rutin acted as a quercetin deliverer to the large intestine and its anti-inflammatory action in TNBS-induced colitis rats may be through quercETin-mediated inhibition of TNF-α-induced NFκB activation.
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Angiotensin II-induced differentiation of adipose tissue-derived mesenchymal stem cells to smooth muscle-like cells
TL;DR: The results suggest that Ang II induces differentiation of human adipose tissue-derived mesenchymal stem cells to contractile smooth muscle-like cells through ERK-dependent activation of the autocrine TGF-beta1-Smad2 crosstalk pathway.
Journal ArticleDOI
A Rho Kinase/Myocardin-Related Transcription Factor-A–Dependent Mechanism Underlies the Sphingosylphosphorylcholine-Induced Differentiation of Mesenchymal Stem Cells Into Contractile Smooth Muscle Cells
TL;DR: The results suggest that SPC induced differentiation of hADSCs into contractile SMCs through a mechanism involving RhoA/Rho kinase–dependent nuclear translocation of MRTF-A, and pharmacological inhibition of Rho Kinase blocked this effect.