Management of non-neurogenic male lower urinary tract symptoms (LUTS), incl. benign prostatic obstruction (BPO)

https://www.europeanurology.com/article/S0302-2838(11)00738-X/pdf/contemporary-management-of-lower-urinary-tract-disease-with-botulinum-toxin-a-a-systematic-review-of-botox-onabotulinumtoxina-and-dysport-abobotulinumtoxina

Contemporary Management of Lower Urinary Tract Disease With Botulinum Toxin A: A Systematic Review of Botox (OnabotulinumtoxinA) and Dysport (AbobotulinumtoxinA)

Surgery for urinary incontinence in women

The present invention provides a nonaqueous electrolytic solution capable of improving electrochemical characteristics at high temperatures and further capable of not only improving a capacity retention rate after a high-temperature cycle test but also decreasing a rate of increase of an electrode thickness, and also to provide an energy storage device using the same. A nonaqueous electrolytic solution having an electrolyte salt dissolved in a nonaqueous solvent, the nonaqueous electrolytic solution containing from 0.001 to 5% by mass of a diisocyanate compound represented by OCN-L-NCO (in the formula, L represents an alkylene group having from 4 to 12 carbon atoms) and further containing from 0.001 to 5% by mass of at least one selected from a specified phosphoric acid ester compound, a specified cyclic sulfonic acid ester compound, a specified isocyanate compound having an ester structure, and a specified triple bond-containing compound, and an energy storage device using the same, are disclosed.

Non-aqueous electrolyte solution and electricity-storage device using same

The Application of Botulinum Toxin in the Prostate

Augmentation of the body contour by localized injection of hard and soft paraffin rose to a zenith of popularity in the early 1900s, whereafter the severe destructive consequences of such injections became widely recognized. However in Korea, these injections are still performed much by nonmedical person. Paraffin or other mineral oil injection into body is no more a useful method to change body contour. We reviewed 26 cases of sclerosing lipogranuloma of penis with complications in recent 13 years after mean 18.5 months from previous injection of paraffin or vaseline. We conclude that the public should be informed of detrimental effects of paraffin injections and that the best treatment of penile paraffinoma is complete excision and appropriate penoplasty.

/pdf/paraffinoma-of-the-penis-37mackc6hb.pdf

Paraffinoma of the penis

The purpose of this study was to evaluate the effect and investigate the putative mechanism of botulinum toxin type A (BTA) applied to the treatment of benign prostatic hyperplasia (BPH). A total of 52 patients with symptomatic BPH were evaluated. Transperineal intraprostatic injection under transrectal ultrasonography was carried out. BTA dissolved in 4 to 9 mL of saline was used from 100 U to 300 U, according to prostate volume. Twenty-six patients received only BTA (BT group), and 26 received both BTA and one month of an alpha-adrenergic antagonist (BTalpha group). The therapeutic outcomes were evaluated by comparing parameters such as international prostate symptom score (IPSS), quality of life, prostate specific antigen, prostate volume, post-void residual urine, and peak urinary flow rate. At the one month follow- up, 18 patients in the BT group and 21 in the BTalpha group had subjective symptomatic relief (p = 0.337). Only IPSS5 (weak stream) was significantly different between the BT group and BTalpha groups (p = 0.034). At the three month follow-up, 39 patients had subjective symptomatic relief. The storage symptoms were improved more than the voiding symptoms. Additionally, about 50 percent of the patients whose voiding symptom improved expressed improved erectile function. BTA injection seems to be an alternative treatment for BPH. The differences after the one month evaluation between the BT and the BTalpha groups might suggest that the adrenergic influence could be relatively reinforced by the anticholinergic effect of BTA. Nitric oxide would thus be involved in a BTA action mechanism in BPH.

/pdf/evaluation-of-short-term-clinical-effects-and-presumptive-xgdjn5iix5.pdf

Evaluation of Short Term Clinical Effects and Presumptive Mechanism of Botulinum Toxin Type A as a Treatment Modality of Benign Prostatic Hyperplasia

The use of a gracilis myocutaneous flap to overlay an extensively traumatized scrotoperineal soft tissue defect, through which both testes and the ruptured bulbous urethra were exposed, is discussed The transplanted gracilis myocutaneous flap, which included vascularized and innervated tissue, was well taken and covered the perineal defect, exposed testes and urethral stricture both cosmetically and functionally

Gracilis myocutaneous flap for the coverage of an extensive scrotoperineal defect and protection of the ruptured urethra and testes.

Reconfigured sigmoid colon neourethra: Substitution of refractory posterior urethral stricture

To identify the clinicopathological events including nm23 expression that underlies progression in renal cell carcinoma, a retrospective analysis of patients with renal cell carcinoma was performed. Ninety-eight cases of radical nephrectomies with extensive regional or para-aortic lymph node dissection were assessed for clinicopathological variables, and eighty-five cases underwent nm23/NDPK-A protein immunohistochemical staining. Significant parameters in survival were tumor size, histologic pattern, Fuhrman's nuclear grade, pathologic T(pT) stage, pathologic N stage, M stage, tumor thrombi, location of metastasis, and nm23 staining intensity. To assess the relationship with survival, the tumors with low and high nm23 expressions were compared. The fifty-nine patients with a high staining intensity had a significantly worse survival than did the twenty-six with a low staining intensity (p = 0.0015). Additionally nm23 staining intensity was correlated with tumor size, Fuhrman's nuclear grade, pT, and distant metastasis. Therefore, the immunostaining intensity of nm23 protein could be used as a prognostic parameter with an inverse correlation.

/pdf/analysis-of-nm23-expression-as-a-prognostic-parameter-in-2kraixxyfh.pdf

Young Tae Lee

Papers

Paraffinoma of the penis

Evaluation of Short Term Clinical Effects and Presumptive Mechanism of Botulinum Toxin Type A as a Treatment Modality of Benign Prostatic Hyperplasia

Gracilis myocutaneous flap for the coverage of an extensive scrotoperineal defect and protection of the ruptured urethra and testes.

Reconfigured sigmoid colon neourethra: Substitution of refractory posterior urethral stricture

Analysis of nm23 expression as a prognostic parameter in renal cell carcinoma.