Y
Yu Chi Chang
Researcher at Johns Hopkins University
Publications - 2
Citations - 293
Yu Chi Chang is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Human genome & Transcriptional noise. The author has an hindex of 2, co-authored 2 publications receiving 213 citations.
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Journal ArticleDOI
CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise
Mihaela Pertea,Mihaela Pertea,Alaina Shumate,Alaina Shumate,Geo Pertea,Ales Varabyou,Ales Varabyou,Florian P. Breitwieser,Yu Chi Chang,Anil K. Madugundu,Akhilesh Pandey,Akhilesh Pandey,Steven L. Salzberg +12 more
TL;DR: The sequences from deep RNA sequencing experiments by the Genotype-Tissue Expression (GTEx) project are assembled to create a new catalog of human genes and transcripts, called CHESS, revealing a heretofore unappreciated amount of transcriptional noise in human cells.
Posted ContentDOI
Thousands of large-scale RNA sequencing experiments yield a comprehensive new human gene list and reveal extensive transcriptional noise
Mihaela Pertea,Alaina Shumate,Geo Pertea,Ales Varabyou,Yu Chi Chang,Anil K. Madugundu,Anil K. Madugundu,Akhilesh Pandey,Steven L. Salzberg +8 more
TL;DR: Over 30 million additional transcripts are detected at more than 650,000 sites, nearly all of which are likely to be nonfunctional, revealing a heretofore unappreciated amount of transcriptional noise in human cells.