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Yuan-Lin Dong
Researcher at University of Texas Medical Branch
Publications - 21
Citations - 796
Yuan-Lin Dong is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Calcitonin gene-related peptide & Myometrium. The author has an hindex of 13, co-authored 18 publications receiving 777 citations. Previous affiliations of Yuan-Lin Dong include University of Texas at Austin.
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Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of human uterine contractility during pregnancy.
TL;DR: Biochemical assays show that the nitric oxide-cyclic guanosine monophosphate system exists in the human uterus and that it inhibits contractility, and the relaxation responsiveness to Nitric oxide is elevated during pregnancy and decreased during labor.
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Role and Regulation of Nitric Oxide in the Uterus During Pregnancy and Parturition
TL;DR: Uterine NO may play a role in maintaining uterine quiescence during pregnancy and steroid hormones, and prostaglandins modulate both the generation and the effects of NO on the uterus.
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Differential expression of cyclooxygenase-1 and -2 proteins in rat uterus and cervix during the estrous cycle, pregnancy, labor and in myometrial cells
TL;DR: It is proposed that increased expression of COX-2 may be involved at term in increased uterine contractility and cervical ripening.
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Calcitonin gene-related peptide reverses the hypertension and significantly decreases the fetal mortality in pre-eclampsia rats induced by NG-nitro-L-arginine methyl ester
TL;DR: The data indicate the CGRP participates in regulation of the vascular adaptations that occur during normal pregnancy, has beneficial effects on the hypertension and increased mortality of experimental preeclampsia, and may exert differential effects onThe systemic and fetal components of utero-placental circulation.
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Involvement of calcitonin gene-related peptide in the modulation of human myometrial contractility during pregnancy.
Yuan-Lin Dong,Li Fang,Sudhir Kondapaka,Pandu R. Gangula,Sunil J. Wimalawansa,Chandrasekhar Yallampalli +5 more
TL;DR: It is concluded that increased CGRP-Rs in myometrium, and resulting enhanced myometrial sensitivity to C GRP, may play a role in maintaining humanMyometrium in a quiescent state during pregnancy, and that a decline in the CGRp-Rs at term could contribute to the initiation of labor.