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Yuanyuan Wu
Researcher at Third Military Medical University
Publications - 15
Citations - 1000
Yuanyuan Wu is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Cell growth & Oncogene. The author has an hindex of 9, co-authored 13 publications receiving 797 citations.
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Journal ArticleDOI
Regulation of autophagy by the Rab GTPase network
X Ao,L Zou,Yuanyuan Wu +2 more
TL;DR: New findings regarding the involvement of Rabs in autophagy are summarized and insights regarding future research on the mechanisms of autophagic regulation are provided.
Journal ArticleDOI
Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma
TL;DR: The data suggest that MALAT1 serves as an oncogene in ESCC, and it regulates ESCC growth by modifying the ATM-CHK2 pathway and it seems that the gene amplification in tumor tissues emerges during ESCC progression, but is not derived from germline origins.
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LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.
Yan Liang,Xuedan Chen,Yuanyuan Wu,Juan Li,Shixin Zhang,Kai Wang,Xingying Guan,Kang Yang,Yun Bai +8 more
TL;DR: The research reveals the prognostic and pro-metastatic roles for CASC9 in ESCC, suggesting that CASC 9 could serve as a biomarker for prognosis and a target for metastasis treatment.
Journal ArticleDOI
Up-regulation of lncRNA CASC9 promotes esophageal squamous cell carcinoma growth by negatively regulating PDCD4 expression through EZH2.
Yuanyuan Wu,Liwen Hu,Liwen Hu,Yan Liang,Juan Li,Kai Wang,Xuedan Chen,Hui Meng,Xingying Guan,Kang Yang,Yun Bai +10 more
TL;DR: This study demonstrates that lncRNA CASC9 functions as an oncogene by negatively regulating PDCD4 expression through recruiting EZH2 and subsequently altering H3K27me3 level, and implicates lnc RNA CASC 9 as a valuable biomarker for ESCC diagnosis and prognosis.
Journal ArticleDOI
A novel long noncoding RNA linc00460 up-regulated by CBP/P300 promotes carcinogenesis in esophageal squamous cell carcinoma.
Yan Liang,Yuanyuan Wu,Xuedan Chen,Shixin Zhang,Kai Wang,Xingying Guan,Kang Yang,Juan Li,Yun Bai +8 more
TL;DR: It is suggested that linc00460 works as an oncogene and might be a valuable prognostic biomarker for ESCC diagnosis and treatment.