scispace - formally typeset
Search or ask a question

Showing papers by "Yutaka Yamaguchi published in 2014"


Journal ArticleDOI
TL;DR: A rare case of recurrent proliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits (PGNMID) deposits that progressed rapidly to allograft failure after kidney transplantation.
Abstract: We present a case of recurrent proliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits (PGNMID) that progressed rapidly to allograft failure. A 56-year-old man had progressed to end-stage renal failure within 1 year after the diagnosis of membranoproliferative glomerulonephritis (MPGN) by kidney biopsy. He underwent living donor kidney transplantation from his brother 6 months later. Serial allograft biopsies revealed early glomerular deposition of IgG, C1q, and C3 at post-operative day 26, and gradual progression of the glomerular deposition and histology of glomerulonephritis. Several immunosuppressive therapies did not prevent proteinuria, microhematuria, and graft dysfunction, and the patient returned to hemodialysis at 7 months after transplantation. Retrospectively, we demonstrated monoclonal IgG3κ deposition in the native and allograft kidney, and the patient was diagnosed with recurrent PGNMID. The serial graft biopsies revealed the pathological details of the progression of PGNMID. This is a rare case of PGNMID that recurred and progressed rapidly to graft failure after kidney transplantation.

9 citations


Journal ArticleDOI
TL;DR: The unique case of a 59‐year‐old man who underwent living kidney transplantation for IgA nephropathy and developed progressive kidney failure associated with the appearance of proliferative glomerulonephritis with monoclonal IgG deposits is described.
Abstract: We herein describe the unique case of a 59-year-old man who underwent living kidney transplantation for IgA nephropathy (IgAN) and developed progressive kidney failure associated with the appearance of proliferative glomerulonephritis. An early protocol biopsy revealed recurrent IgAN with mesangial IgA2 deposits restricted to a single immunoglobulin λ light-chain isotype. Despite treatment with tonsillectomy and rituximab, the patient eventually lost his allograft 31 months after transplantation. Serum electrophoresis showed a monoclonal IgA pattern. This case might share common pathological characteristics with the newly described entity referred to as proliferative glomerulonephritis with monoclonal IgG deposits.

9 citations


Patent
18 Dec 2014
TL;DR: In this paper, the authors proposed a metal bat for hardball baseball, which includes a ball batting part 1, a cap 2 connected to a tip end side of the ball hitting part 1 with respect to the tapered part 3, and a grip 4 provided at an opposite side of a hardball hitting part hitting part 2.
Abstract: PROBLEM TO BE SOLVED: To provide a metal bat for hardball baseball capable of significantly enhancing a batted ball speed.SOLUTION: The metal bat for the hardball baseball includes: a ball batting part 1; a cap 2 connected to a tip end side of the ball batting part 1; a tapered part 3 provided at a rear end side of the ball batting part 1; and a grip 4 provided at an opposite side of the ball hitting part 1 with respect to the tapered part 3. A moment of inertia evaluation value Igrip around the grip 4 is 2.26 kg cm sor less. A ratio of a distance from a center CP of percussion of the metal bat for hardball baseball to a rear end 41 of the grip 4, to a distance from a tip end 21 of the cap 2 is 0.828 or more.

1 citations