Zachary Cole Sonner

TL;DR: Reports here are microfluidic models for eccrine sweat generation and flow which are coupled with review of blood-to-sweat biomarker partition pathways, therefore providing insights such as how biomarker concentration changes with sweat flow rate.

TL;DR: Integration of sudomotor axon reflex sweat stimulation for continuous wearable sweat analyte analysis, including the ability for side-by-side integration of chemical stimulants & sensors without cross-contamination is reported.

Abstract: A sweat sensing device (28) includes a plurality of sweat collection pads (40, 42, and 44) communicating with a sensor (36). Each of the pads (40, 42, and 44) is activated by electronics (34) that include a timing circuit which allows one or more of the pads (40, 42, and 44) to be activated at a selected time and subsequent deactivated after a defined period of time. This allows for selective collection of sweat from a plurality of pads over a prolonged period of time. Further, the devices can use a common microfluidic device (38) which both transports sweat activating substance, such as pilocarpine, to the surface of the skin (12) and directs sweat away from the skin (12) to a sensing device (28).

TL;DR: In this paper, a micro-porous membrane is constructed such that it is porous to sweat only, and the spreading of sweat is isolated to only regions above the sweat glands before it reaches the sensors.

TL;DR: In this article, a sweat sensing device (20) comprises at least one sweat generation unit (22) capable of initiating sudomotor axon reflex (SAR) sweating in an indirect stimulation region.