A sensor chip includes: a substrate that has a planar portion; and a diffraction grating, on which a target substance is placed, that includes a plurality of first protrusions periodically arranged in a period equal to or greater than 100 nm and equal to or less than 1000 nm in a first direction that is parallel to the planar portion, a plurality of base portions that is located between two of the first protrusions adjacent to each other and configures a base of the substrate, and a plurality of second protrusions that is formed on upper faces of the plurality of the first protrusions, has a surface formed from a metal, and is formed on the planar portion

Sensor chip, sensor cartridge, and analysis apparatus

A surface-enhanced Raman scattering element comprises a substrate having a principal surface; a molded layer having a support part formed on the principal surface of the substrate so as to extend along the principal surface and a fine structure part formed on the support part; and a conductor layer formed on the fine structure part and constituting an optical functional part for generating surface-enhanced Raman scattering; the molded layer being relatively thinner in a direction intersecting the principal surface of the substrate at a center edge part of a fine structure area formed with the fine structure part in the molded layer than at an outer edge part of the fine structure area.

Surface-enhanced raman scattering element

A polarization element includes: a base; a plurality of metal thin wires provided on the base along a predetermined alignment axis; and a plurality of protection films covering each of the plurality of metal thin wires. In the element, each of the protection films covers an upper end and both sidewalls of one of the metal thin wires. Further, a width of a part, which is on the upper end of the one of the metal thin wires, of the each of the protection films in a direction of the alignment axis is larger than a width obtained by summing a width of the one of the metal thin wires in the direction of the alignment axis and widths of parts, which are on the both sidewalls of the one of the metal thin wires, of the each of the protection films in the direction of the alignment axis. The protection films on sidewalls, which are opposed to each other, of the metal thin wires that are adjacent form an air gap.

Polarization element, method for manufacturing the same, liquid crystal device, and electronic apparatus

[Problem] The purpose of the present invention is to provide an optical-electric-field enhancement device that can detect Raman-scattered light with higher sensitivity. [Solution] An optical-electric-field enhancement device (1) includes: a transparent substrate (10) having, on the surface thereof, a transparent structure with fine projections and recesses (22); and a metal film (24) formed on the surface of the structure with fine projections and recesses (22), which is provided on the surface of the transparent substrate. Thus, irradiation with excitation light (L1) and the detection of light to be detected (L2) can be performed from either the front surface side of the metal film (24) or the back surface side of the transparent substrate (10).

Optical-electric-field enhancement device

PROBLEM TO BE SOLVED: To provide an optical device capable of increasing the density of metal nanoparticles acting as a hot site through determining a "wave number" of a propagation surface plasmon PSP without relying on an array period of the metal nanoparticles while using the propagation surface plasmon and a localized surface plasmon in combination, and a detector using the optical device.SOLUTION: An optical device 100A, or 100B comprises: a projection group 110 projecting from a conductor surface 102 of a substrate 100 and arranged along first direction X at a period Px; a dielectric layer 120 covering the conductor surface and the projection group; and a metal nanostructure 130 formed by arranging metal nanoparticle 130A whose size d is in a nano-level along the first direction on the dielectric layer. In the optical device, λ>Px>d is satisfied, where λ denotes the wavelength of irradiation light, and Px>px is satisfied, where the maximal value of an array pitch of two metal nanoparticles adjacent to each other in the first direction is px.

Optical device and detector

PROBLEM TO BE SOLVED: To provide a surface plasmon exciting intensified fluorescent microscope and the fluorescent microplate reader with a simple optical system capable of simple operation and capable of realizing highly sensitive fluorescence detection by utilizing the ready existing fluorescent microscope or the fluorescent microplate reader. SOLUTION: The fluorescent microscope (1) or the fluorescent microplate reader is provided with the microplate (4) mounting the specimen (A) which is the object of the observation. The microplate (4) is provided with the base plate which has a periodic structure on the surface, the metallic layer formed on the periodic structure, and the protection layer formed on the metallic layer. The metallic layer is made of metal and capable of generating surface plasmon. The light (L) is entered into the microplate (4) from the protection layer side to generate the surface plasmon resonance light. COPYRIGHT: (C)2009,JPO&INPIT

Microplate with periodic structure and surface plasmon exciting intensified fluorescent microscope using the same or fluorescent microplate reader

PROBLEM TO BE SOLVED: To measure a trace material with high sensitivity, by further improving the performance of an element used for detecting the trace material with high sensitivity, by using localized plasmon resonance. SOLUTION: This trace material detection element utilizing plasmon resonance has a substrate; a plurality of fine projection parts or fine pores formed on one surface of the substrate; and a metal layer formed on the upper surface of the projection parts and on the substrate surface, or a metal layer formed on a peripheral part and the bottom surface of the fine pores. In the trace material detection element, the metal layer formed on the upper surface of the projection parts is in a noncontact state with the metal layer formed on the substrate surface, or the metal layer formed on the peripheral part of the fine pores is in a noncontact state, with the metal layer being formed on the bottom surface of the fine pores. COPYRIGHT: (C)2010,JPO&INPIT

Trace material detection element

PROBLEM TO BE SOLVED: To provide an inexpensive surface plasmon excitation enhanced fluorescence microscope that can be operated easily by a simple optical system and can detect fluorescence with high sensitivity by utilizing an existing fluorescence microscope and a fluorescence microplate reader, and to provide a fluorescence microplate reader. SOLUTION: In the fluorescence microscope (1) having a microplate (4) for mounting a sample (A) to be measured or the fluorescence microplate reader, the microplate (4) includes a base substrate having a periodic structure on the surface, a metal layer formed on the periodic structure of the base substrate, and a quenching suppression layer formed on the metal layer. The metal layer is formed by metal capable of generating surface plasmon. Light (Li) is allowed to enter the microplate (4) from the side of the base substrate to generate surface plasmon resonance light (Lp) at the side of the quenching suppression layer, which is set to be an excitation field of a fluorescence molecule adsorbed and bonded to the surface of the quenching suppression layer so that enhanced fluorescence can be observed. COPYRIGHT: (C)2010,JPO&INPIT

Microplate having periodic structure, surface plasmon excitation enhanced fluorescence microscope using the same, fluorescence microplate reader, and method of detecting specific antigen/antibody reaction

PROBLEM TO BE SOLVED: To provide an optical element having a high flexibility in a periodical structure and to provide an optical demultiplexer which has high wavelength resolution and little dependence on polarization and which can be made small in size. SOLUTION: A planar optical circuit type optical demultiplexer having a diffraction grating 30 and concave mirrors 33, 35 fabricated on one substrate 38 is provided. The grating 30 is formed by periodically arranging a solid ridge part and a space of a groove part, and is embedded in a solid material to have an optical waveguide structure. The planar optical circuit can be easily manufactured usually by lithography, etching and film deposition techniques. The optical demultiplexer to be used for low-density wavelength multiplex system for optical communication is small-sized, requires a small space for installation, and satisfies the conditions that it has high durability against temperature or humidity and excellent stability and that it can be mass produced. COPYRIGHT: (C)2005,JPO&NCIPI

Optical element, and optical circuit and optical demultiplexer having same

PROBLEM TO BE SOLVED: To provide an optical multilayer film combined element having an excellent optical characteristic SOLUTION: The optical multilayer film element of the present invention is provided with: a first multilayer film formed by laminating materials having different refraction indices, and having a SiO 2 layer at least on one face; and a second multilayer film formed by laminating materials having different refraction indices and having a SiO 2 layer at least on one face The SiO 2 layers of the first and the second multilayer films are bonded together with a chemical binding reacted by using a chemical including hydrofluoric acid COPYRIGHT: (C)2006,JPO&NCIPI

準治西井

Papers

Microplate with periodic structure and surface plasmon exciting intensified fluorescent microscope using the same or fluorescent microplate reader

Trace material detection element

Microplate having periodic structure, surface plasmon excitation enhanced fluorescence microscope using the same, fluorescence microplate reader, and method of detecting specific antigen/antibody reaction

Optical element, and optical circuit and optical demultiplexer having same

Optical multilayer film element

準治 西井

Papers

Microplate with periodic structure and surface plasmon exciting intensified fluorescent microscope using the same or fluorescent microplate reader

Trace material detection element

Microplate having periodic structure, surface plasmon excitation enhanced fluorescence microscope using the same, fluorescence microplate reader, and method of detecting specific antigen/antibody reaction

Optical element, and optical circuit and optical demultiplexer having same

Optical multilayer film element

準治西井