Z
Zichun Xiang
Researcher at Peking Union Medical College
Publications - 36
Citations - 4273
Zichun Xiang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Respiratory tract infections & Innate immune system. The author has an hindex of 15, co-authored 31 publications receiving 2837 citations.
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ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3
Cong Yu,Bei Wang,Yue Zhu,Chongyang Zhang,Lili Ren,Xiaobo Lei,Zichun Xiang,Zhuo Zhou,He Huang,Jianwei Wang,Zhendong Zhao +10 more
TL;DR: The findings establish ID2 as a modulator of IRF3 activation induced by TBK1 and/or IKKε but also introduce a mechanism for cross-talk between innate immunity and cell development and differentiation.