Zofia Zwolska

TL;DR: A DNA sequencing-based method used to detect mutations in the genome of drug-resistant Mycobacterium tuberculosis is useful for rapid detection of multiple-drug-resistant M. tuberculosis and for identifying novel mutations in drug- resistant M.culosis.

TL;DR: A total of 105 rifampin (RMP)-and/or isoniazid (INH)-resistant strains of Mycobacterium tuberculosis isolated from different parts of Poland in 2000 were screened for mutations associated with resistance to these drugs by two molecular methods, namely sequence analysis and real-time PCR technology as discussed by the authors.

TL;DR: It is demonstrated that not whole Mycobacterium tuberculosis but its particular antigens, hSp70Mtb, hsp65MTb, and hsp16MtB are present in lymph node tissues of patients with sarcoidosis (SA).

TL;DR: The investigations of new pyrazine and pyridine derivatives showing an antibacterial activity have been made and they appeared to be of elevated activity towards the anaerobes and of low one towards the aerobes.

TL;DR: This study evaluated eight different mutations identified in an 81 bp section of a "hot spot" region of the rpo B gene of RMP resistant Mycobacterium tuberculosis clinical strains and found that some mutations require a specific genetic background for the host strain to develop resistance to rifampin.