Institution
Alice Springs Hospital
Healthcare•
About: Alice Springs Hospital is a healthcare organization based out in . It is known for research contribution in the topics: Citation & Computer science. The organization has 6 authors who have published 14 publications receiving 7 citations.
Topics: Citation, Computer science, Medicine, Gene, Internal medicine
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TL;DR: In this paper , the performance characteristics of polymerase chain reaction (PCR), interleukin-6 (IL6), and calprotectin of synovial fluid in the diagnosis of periprosthetic joint infection (PJI) were investigated.
Abstract: The preoperative diagnosis of periprosthetic joint infection (PJI) remains a challenge due to a lack of biomarkers that are both sensitive and specific. We investigated the performance characteristics of polymerase chain reaction (PCR), interleukin-6 (IL6), and calprotectin of synovial fluid in the diagnosis of PJI.We performed systematic search of PubMed, Embase, The Cochrane Library, Web of Science, and Science Direct from the date of inception of each database through to 31 May 2021. Studies which described the diagnostic accuracy of synovial fluid PCR, IL6, and calprotectin using the Musculoskeletal Infection Society criteria as the reference standard were identified.Overall, 31 studies were identified: 20 described PCR, six described IL6, and five calprotectin. The sensitivity and specificity were 0.78 (95% confidence interval (CI) 0.67 to 0.86) and 0.97 (95% CI 0.94 to 0.99), respectively, for synovial PCR;, 0.86 (95% CI 0.74 to 0.92), and 0.94 (95% CI 0.90 to 0.96), respectively, for synovial IL6; and 0.94 (95% CI 0.82 to 0.98) and 0.93 (95% CI 0.85 to 0.97), respectively, for synovial calprotectin. Likelihood ratio scattergram analyses recommended clinical utility of synovial fluid PCR and IL6 as a confirmatory test only. Synovial calprotectin had utility in the exclusion and confirmation of PJI.Synovial fluid PCR and IL6 had low sensitivity and high specificity in the diagnosis of PJI, and is recommended to be used as confirmatory test. In contrast, synovial fluid calprotectin had both high sensitivity and specificity with utility in both the exclusion and confirmation of PJI. We recommend use of synovial fluid calprotectin studies in the preoperative workup of PJI. Cite this article: Bone Joint J 2022;104-B(3):311-320.
7 citations
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TL;DR: Cate Swannell et al. as mentioned in this paper reviewed their Terms and Conditions of Use and check box below to share full-text version of article and provided a link to share a link with friends and colleagues.
Abstract: Medical Journal of AustraliaVolume 216, Issue 9 p. 436-437 News News briefs Cate Swannell, Cate SwannellSearch for more papers by this author Cate Swannell, Cate SwannellSearch for more papers by this author First published: 15 May 2022 https://doi.org/10.5694/mja2.51514Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume216, Issue9May 2022Pages 436-437 RelatedInformation
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TL;DR: Cate Swannell et al. as discussed by the authors reviewed the Terms and Conditions of Use and check box below to share full-text version of article and provided a link to share a fulltext version with colleagues.
Abstract: Medical Journal of AustraliaVolume 216, Issue 2 p. 59-60 News News briefs Cate Swannell, Cate SwannellSearch for more papers by this author Cate Swannell, Cate SwannellSearch for more papers by this author First published: 06 February 2022 https://doi.org/10.5694/mja2.51401Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. Volume216, Issue2February 2022Pages 59-60 RelatedInformation
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TL;DR: Cate Swannell et al. as discussed by the authors reviewed their Terms and Conditions of Use and check box below to share full-text version of article and provided a link to share a link with friends and colleagues.
Abstract: Medical Journal of AustraliaVolume 216, Issue 4 p. 165-166 News News briefs Cate Swannell, Cate SwannellSearch for more papers by this author Cate Swannell, Cate SwannellSearch for more papers by this author First published: 06 March 2022 https://doi.org/10.5694/mja2.51413Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume216, Issue4March 2022Pages 165-166 RelatedInformation
Authors
Showing all 6 results
Name | H-index | Papers | Citations |
---|---|---|---|
Dalila Ivanković | 1 | 1 | 7 |
Michael S. Niederman | 1 | 1 | 7 |
Munirah A. Almessiere | 0 | 1 | 0 |
Iryna Yan | 0 | 8 | 0 |
Yanfeng Chu | 0 | 2 | 0 |
Natascha Müller | 0 | 1 | 0 |